Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
Breast Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
SET Domain-Containing Protein 4 Epigenetically Controls Breast Cancer Stem Cell Quiescence.
|
31308046 |
2019 |
Carcinogenesis
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
These results suggest that Setd4 has a critical role in modulating lymphomagenesis and may be targeted to suppress radiation-induced carcinogenesis.
|
31794893 |
2020 |
Carcinogenesis
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
SETD4-defined qBCSCs had a high tumorigenesis potential and correlated with malignancy and chemotherapy resistance in clinical breast cancer patients.
|
31308046 |
2019 |
Cognition Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Our results revealed the high levels of complexities of gene actions and interactions associated with the Setd4/Cbr1-Fam3b/Mx2 region as well as their relationship with developmental cognitive deficits in DS.
|
26374847 |
2015 |
Colorectal Carcinoma
|
0.300 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
Complete Trisomy 21 Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our results revealed the high levels of complexities of gene actions and interactions associated with the Setd4/Cbr1-Fam3b/Mx2 region as well as their relationship with developmental cognitive deficits in DS.
|
26374847 |
2015 |
Down Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our results revealed the high levels of complexities of gene actions and interactions associated with the Setd4/Cbr1-Fam3b/Mx2 region as well as their relationship with developmental cognitive deficits in DS.
|
26374847 |
2015 |
Impaired cognition
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our results revealed the high levels of complexities of gene actions and interactions associated with the Setd4/Cbr1-Fam3b/Mx2 region as well as their relationship with developmental cognitive deficits in DS.
|
26374847 |
2015 |
Leukemogenesis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
However, in Tp53 deficient mice, Setd4 deletion did not delay the radiation-induced lymphomagenesis although it accelerated the spontaneous T-lymphomagenesis in non-irradiated mice.
|
31794893 |
2020 |
Malignant neoplasm of breast
|
0.010 |
Biomarker
|
disease |
BEFREE |
SET Domain-Containing Protein 4 Epigenetically Controls Breast Cancer Stem Cell Quiescence.
|
31308046 |
2019 |
Malignant neoplasm of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
SETD4-defined quiescent CSCs were present in multiple cancer types including gastric, cervical, ovarian, liver, and lung cancers and were resistant to chemotherapy.
|
31308046 |
2019 |
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
SETD4-defined qBCSCs had a high tumorigenesis potential and correlated with malignancy and chemotherapy resistance in clinical breast cancer patients.
|
31308046 |
2019 |
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
SETD4-defined qBCSCs were resistant to chemoradiotherapy and promoted tumor relapse in a mouse model.
|
31308046 |
2019 |
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
SETD4-defined qBCSCs had a high tumorigenesis potential and correlated with malignancy and chemotherapy resistance in clinical breast cancer patients.
|
31308046 |
2019 |
Thymic Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Loss of Setd4 delays radiation-induced thymic lymphoma in mice.
|
31794893 |
2020 |