|
Acute gastroenteritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
This study shows that all known non-SARS HCoVs can be found in stools of children with acute gastroenteritis.
|
20233673 |
2010 |
|
Adult Liver Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Ultrasensitive Detection of Serum MicroRNA Using Branched DNA-Based SERS Platform Combining Simultaneous Detection of α-Fetoprotein for Early Diagnosis of Liver Cancer.
|
30238748 |
2018 |
|
Alkalosis
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Missense mutations in the mitochondrial seryl-tRNA synthetase gene, SARS2, have been identified in HUPRA syndrome (hyperuricemia, pulmonary hypertension, renal failure in infancy, and alkalosis).
|
27279129 |
2016 |
|
Anemia
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
|
Aortic Valve Insufficiency
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
These emerging infections, including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV) and the pandemic influenza A(H1N1) and avian influenza (AI) viruses, have seriously threatened global health and the economy.
|
30985968 |
2019 |
|
Atypical pneumonia
|
0.030 |
Biomarker
|
disease |
BEFREE |
A novel coronavirus has been associated with a worldwide outbreak of atypical pneumonia referred to as Severe Acute Respiratory Syndrome (SARS-CoV).
|
15163419 |
2004 |
|
Atypical pneumonia
|
0.030 |
Biomarker
|
disease |
BEFREE |
Among the multiple organ disorders caused by the severe acute respiratory syndrome coronavirus (SARS-CoV), acute lung failure following atypical pneumonia is the most serious and often fatal event.
|
19112100 |
2009 |
|
Atypical pneumonia
|
0.030 |
Biomarker
|
disease |
BEFREE |
Severe acute respiratory syndrome coronavirus (SARS-CoV) infects many organs, such as lung, liver, and immune organs and causes life-threatening atypical pneumonia, SARS causes high morbidity and mortality rates.
|
17705188 |
2007 |
|
Brain Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Our results show that neurons are a highly susceptible target for SARS-CoV and that only the absence of the host cell receptor prevents severe murine brain disease.
|
18495771 |
2008 |
|
Breast Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Successful detection and delineation of pulmonary micrometastatic lesions as small as 200 μm, corroborated by histology, immunohistochemistry, and bioluminescence imaging confirmed the suitability of both TF as a target and αTF-SERRS-NPs as an effective contrast agent for imaging breast cancer lung metastases.
|
27991632 |
2017 |
|
Breast Carcinoma
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Synthesis and characterization of SERS gene probe for BRCA-1 (breast cancer).
|
16833124 |
2006 |
|
Bronchitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The observed cross-reactivity is not a consequence of a higher level of amino acid identity between SARS-CoV and porcine CoV nucleoproteins, because sequence comparisons indicated that SARS-CoV N protein has amino acid identity similar to that of infectious bronchitis virus N protein and shares a higher level of identity with bovine CoV N protein within the cross-reactive region.
|
17913799 |
2007 |
|
Carcinoma of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
Enzyme-Driven Switchable Fluorescence-SERS Diagnostic Nanococktail for the Multiplex Detection of Lung Cancer Biomarkers.
|
30353718 |
2018 |
|
Carcinoma of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
In the present work, an ultrasensitive SERS sensor was prepared based on an Ag nanorod array SERS substrate by assembling special hairpin-shaped molecular beacons (MBs) for the detection of multiple lung cancer-related miRNA biomarkers.
|
27714088 |
2016 |
|
Carcinoma of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
Ultrasensitive Detection of Circulating Tumor DNA of Lung Cancer via an Enzymatically Amplified SERS-Based Frequency Shift Assay.
|
31050289 |
2019 |
|
Cerebrovascular accident
|
0.010 |
Biomarker
|
group |
BEFREE |
Compared to the pre-SARS period, excess rates of mortality associated with influenza during the post-SARS period in Hong Kong decreased for cardiorespiratory diseases (RR = 0.90, 95% CI 0.80, 1.01), stroke (RR = 0.74, 95% CI 0.50, 1.09), and ischemic heart diseases (RR = 0.45, 95% CI 0.34, 0.58).
|
30764779 |
2019 |
|
Chikungunya Fever
|
0.020 |
Biomarker
|
disease |
BEFREE |
We have reported on aristeromycin (1) and 6'-fluorinated-aristeromycin analogues (2), which are active against RNA viruses such as Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), Zika virus (ZIKV), and Chikungunya virus (CHIKV).
|
31841728 |
2020 |
|
Chikungunya Fever
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
The best examples are the recurring outbreaks of dengue and chikungunya fever in tropical and sub-tropical regions, the recent epidemic of Zika in the Americas and the Caribbean, and the SARS, MERS, and influenza A outbreaks across the globe.
|
28772262 |
2017 |
|
Chronic Kidney Diseases
|
0.100 |
Biomarker
|
group |
HPO |
|
|
|
|
Circling gait
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Personalized detection of circling exosomal PD-L1 based on Fe<sub>3</sub>O<sub>4</sub>@TiO<sub>2</sub> isolation and SERS immunoassay.
|
31678824 |
2020 |
|
Colon Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Interestingly, however, SARS-CoV strongly induced the chemokines IP-10 and IL-8 in the colon carcinoma cell line Caco-2, but not in the embryonic kidney cell line 293.
|
16571117 |
2006 |
|
Colon Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Besides the upregulation of genes associated with apoptosis, which was exactly opposite to the previously reported effect of SARS-CoV in a colonic carcinoma cell line, genes related to inflammation, stress response, and procoagulation were also upregulated.
|
15858003 |
2005 |
|
Common Cold
|
0.030 |
Biomarker
|
disease |
BEFREE |
In marked contrast to their historical classification as relatively harmless, common cold-causing, respiratory pathogens, human coronaviruses (HCoVs) are associated with more severe clinical complications, as emphasized by the discovery of severe acute respiratory syndrome-associated CoV (SARS-CoV) in 2003.
|
19892230 |
2009 |
|
Common Cold
|
0.030 |
Biomarker
|
disease |
BEFREE |
Huh7 cells were found to be susceptible to both SARS-CoV, associated with SARS, and human coronavirus 229E (HCoV-229E), usually associated with the common cold.
|
15858003 |
2005 |
|
Common Cold
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Coronaviruses (CoV) cause common colds in humans, but are also responsible for the recent Severe Acute, and Middle East, respiratory syndromes (SARS and MERS, respectively).
|
29474890 |
2018 |