Kaposi Sarcoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
The vTAs in Kaposi's sarcoma-associated herpesvirus (KSHV) are ORF18, ORF24, ORF30, ORF31, ORF34, and ORF66.
|
30305361 |
2019 |
Kaposi Sarcoma
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
The results show that the KSHV ORF34 protein is involved in the KSHV life cycle by regulating the expression of HIF-1α and HIF-2α proteins.<b>IMPORTANCE</b> Hypoxia inducible factor 1α (HIF-1α) and HIF-2α are transcription factors which play important roles in the Kaposi's sarcoma-associated herpesvirus (KSHV) latent and lytic gene replication.
|
31189709 |
2019 |
Kaposi Sarcoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Kaposi's sarcoma-associated herpesvirus ORF34 is essential for late gene expression and virus production.
|
28336944 |
2017 |
Kaposi Sarcoma
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Kaposi's sarcoma-associated herpesvirus ORF66 is essential for late gene expression and virus production via interaction with ORF34.
|
31694948 |
2020 |
Kaposi Sarcoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
In Kaposi's sarcoma-associated herpesvirus (KSHV), these vTAs are encoded by ORF18, ORF24, ORF30, ORF31, ORF34, ORF66.
|
31578296 |
2020 |
Autistic Disorder
|
0.020 |
Biomarker
|
disease |
BEFREE |
We identify FAM120C as a novel X-linked candidate gene for autism for two reasons: first, a larger deletion encompassing FAM120C segregates with autism in a previously reported family and second, there is recent evidence that FAM120C interacts with CYFIP1, part of the FMRP (Fragile X Mental Retardation Protein) network.
|
25258334 |
2014 |
Autistic Disorder
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our findings show that in addition to point mutations, a complete deletion of the PHF8 gene is associated with the X-linked mental retardation Siderius-Hamel syndrome (OMIM 300263) and further suggest that the larger size of the Xp11.22 deletion including genes FAM120C and WNK3 may be involved in the pathogenesis of autism.
|
18498374 |
2008 |
Pervasive Development Disorder
|
0.010 |
Biomarker
|
group |
BEFREE |
In conclusion, FAM120C is a novel candidate gene for autism spectrum disorder based on genetic evidence and the brain expression pattern.
|
25258334 |
2014 |
Autism Spectrum Disorders
|
0.010 |
Biomarker
|
disease |
BEFREE |
In conclusion, FAM120C is a novel candidate gene for autism spectrum disorder based on genetic evidence and the brain expression pattern.
|
25258334 |
2014 |
Siderius X-linked mental retardation syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Our findings show that in addition to point mutations, a complete deletion of the PHF8 gene is associated with the X-linked mental retardation Siderius-Hamel syndrome (OMIM 300263) and further suggest that the larger size of the Xp11.22 deletion including genes FAM120C and WNK3 may be involved in the pathogenesis of autism.
|
18498374 |
2008 |
Autistic Disorder
|
0.020 |
GeneticVariation
|
disease |
LHGDN |
Our findings show that in addition to point mutations, a complete deletion of the PHF8 gene is associated with the X-linked mental retardation Siderius-Hamel syndrome (OMIM 300263) and further suggest that the larger size of the Xp11.22 deletion including genes FAM120C and WNK3 may be involved in the pathogenesis of autism.
|
18498374 |
2008 |