ARHGAP15, Rho GTPase activating protein 15, 55843

N. diseases: 40; N. variants: 32
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.100 GeneticVariation disease GWASDB Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 17463246 2007
CUI: C0037369
Disease: Smoking
Smoking 		0.100 GeneticVariation phenotype GWASCAT Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 26053186 2015
CUI: C1519383
Disease: Smoking Behaviors
Smoking Behaviors 		0.100 GeneticVariation phenotype GWASCAT Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 26053186 2015
CUI: C0008810
Disease: Circadian Rhythms
Circadian Rhythms 		0.100 GeneticVariation phenotype GWASCAT GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person. 26835600 2016
CUI: C0023508
Disease: White Blood Cell Count procedure
White Blood Cell Count procedure 		0.100 GeneticVariation phenotype GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
CUI: C0200635
Disease: Lymphocyte Count measurement
Lymphocyte Count measurement 		0.100 GeneticVariation phenotype GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
CUI: C4317009
Disease: Diverticular Diseases
Diverticular Diseases 		0.410 Biomarker group CTD_human In the combined Icelandic and Danish data sets we observe significant association of intronic variants in ARHGAP15 (Rho GTPase-activating protein 15; rs4662344-T: P=1.9 × 10<sup>-18</sup>, odds ratio (OR)=1.23) and COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase; rs7609897-T: P=1.5 × 10<sup>-10</sup>, OR=0.87) with diverticular disease and in FAM155A (family with sequence similarity 155A; rs67153654-A: P=3.0 × 10<sup>-11</sup>, OR=0.82) with diverticulitis. 28585551 2017
CUI: C4317009
Disease: Diverticular Diseases
Diverticular Diseases 		0.410 GeneticVariation group GWASCAT In the combined Icelandic and Danish data sets we observe significant association of intronic variants in ARHGAP15 (Rho GTPase-activating protein 15; rs4662344-T: P=1.9 × 10<sup>-18</sup>, odds ratio (OR)=1.23) and COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase; rs7609897-T: P=1.5 × 10<sup>-10</sup>, OR=0.87) with diverticular disease and in FAM155A (family with sequence similarity 155A; rs67153654-A: P=3.0 × 10<sup>-11</sup>, OR=0.82) with diverticulitis. 28585551 2017
CUI: C4317009
Disease: Diverticular Diseases
Diverticular Diseases 		0.410 GeneticVariation group BEFREE In the combined Icelandic and Danish data sets we observe significant association of intronic variants in ARHGAP15 (Rho GTPase-activating protein 15; rs4662344-T: P=1.9 × 10<sup>-18</sup>, odds ratio (OR)=1.23) and COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase; rs7609897-T: P=1.5 × 10<sup>-10</sup>, OR=0.87) with diverticular disease and in FAM155A (family with sequence similarity 155A; rs67153654-A: P=3.0 × 10<sup>-11</sup>, OR=0.82) with diverticulitis. 28585551 2017
CUI: C4505353
Disease: Diverticular Bleeding
Diverticular Bleeding 		0.300 Biomarker disease CTD_human Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis. 28585551 2017
CUI: C0012813
Disease: Diverticulitis
Diverticulitis 		0.110 GeneticVariation disease GWASCAT Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis. 28585551 2017
CUI: C0012813
Disease: Diverticulitis
Diverticulitis 		0.110 GeneticVariation disease BEFREE In the combined Icelandic and Danish data sets we observe significant association of intronic variants in ARHGAP15 (Rho GTPase-activating protein 15; rs4662344-T: P=1.9 × 10<sup>-18</sup>, odds ratio (OR)=1.23) and COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase; rs7609897-T: P=1.5 × 10<sup>-10</sup>, OR=0.87) with diverticular disease and in FAM155A (family with sequence similarity 155A; rs67153654-A: P=3.0 × 10<sup>-11</sup>, OR=0.82) with diverticulitis. 28585551 2017
CUI: C0021704
Disease: Intelligence
Intelligence 		0.100 GeneticVariation phenotype GWASCAT Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence. 28530673 2017
CUI: C0021704
Disease: Intelligence
Intelligence 		0.100 GeneticVariation phenotype GWASCAT Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets. 29186694 2017
CUI: C0017638
Disease: Glioma
Glioma 		0.020 AlteredExpression disease BEFREE We found that there is a correlation between expression of ARHGAP15 and glioma level. 27862679 2017
CUI: C1510475
Disease: Diverticulosis
Diverticulosis 		0.010 GeneticVariation disease BEFREE In the combined Icelandic and Danish data sets we observe significant association of intronic variants in ARHGAP15 (Rho GTPase-activating protein 15; rs4662344-T: P=1.9 × 10<sup>-18</sup>, odds ratio (OR)=1.23) and COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase; rs7609897-T: P=1.5 × 10<sup>-10</sup>, OR=0.87) with diverticular disease and in FAM155A (family with sequence similarity 155A; rs67153654-A: P=3.0 × 10<sup>-11</sup>, OR=0.82) with diverticulitis. 28585551 2017
CUI: C4317009
Disease: Diverticular Diseases
Diverticular Diseases 		0.410 GeneticVariation group GWASCAT Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease. 30177863 2018
CUI: C4317009
Disease: Diverticular Diseases
Diverticular Diseases 		0.410 Biomarker group CTD_human Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease. 30177863 2018
CUI: C4505353
Disease: Diverticular Bleeding
Diverticular Bleeding 		0.300 Biomarker disease CTD_human Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease. 30177863 2018
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.100 GeneticVariation disease GWASCAT Rare and Common Variants Conferring Risk of Tooth Agenesis. 29364747 2018
CUI: C0021704
Disease: Intelligence
Intelligence 		0.100 GeneticVariation phenotype GWASCAT Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. 29844566 2018
CUI: C0021704
Disease: Intelligence
Intelligence 		0.100 GeneticVariation phenotype GWASCAT Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. 29942086 2018
CUI: C0155922
Disease: Tooth development and eruption disorder
Tooth development and eruption disorder 		0.100 GeneticVariation disease GWASCAT Rare and Common Variants Conferring Risk of Tooth Agenesis. 29364747 2018
CUI: C0399352
Disease: Developmental absence of tooth
Developmental absence of tooth 		0.100 GeneticVariation disease GWASCAT Rare and Common Variants Conferring Risk of Tooth Agenesis. 29364747 2018
CUI: C0428883
Disease: Diastolic blood pressure
Diastolic blood pressure 		0.100 GeneticVariation phenotype GWASCAT Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. 30224653 2018