PSEN1, presenilin 1, 5663

N. diseases: 369; N. variants: 155
Disease: clinical depression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2362914
Disease: clinical depression
clinical depression 		0.010 GeneticVariation disease BEFREE Finally, we demonstrate that the two PS-1 variants reported to be associated with an increased incidence of clinical depression [e.g., A431E and L235V] both induce MAO-A activity in HT-22 cells. 21373759 2011