|
Absence of sensation
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
<b>Aim:</b> To clarify the impact of general anaesthesia on cognitive function and to study the possible effect of general anaesthesia on serum S100B, the marker of neuronal degeneration.
|
30590973 |
2019 |
|
Memory impairment
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
<b>Conclusion:</b> General anaesthesia is incriminated in the development of postoperative verbal and visual memory impairment and in the postoperative increase in serum S100B, the markers of neuronal degeneration.
|
30590973 |
2019 |
|
Forgetful
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
<b>Conclusion:</b> General anaesthesia is incriminated in the development of postoperative verbal and visual memory impairment and in the postoperative increase in serum S100B, the markers of neuronal degeneration.
|
30590973 |
2019 |
|
Epilepsy
|
0.220 |
AlteredExpression
|
disease |
BEFREE |
<b>Main outcomes and measures:</b> Peripheral blood levels of S100B in patients with epilepsy compared with controls.
|
31156363 |
2019 |
|
Leptospirosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
<b>Results:</b> The control group differed significantly from the leptospirosis and septic shock patients which demonstrate strong similarities: diffuse congestion in the red pulp with a moderate to intense infiltration of plasma cells and polymorphonuclear cells; follicles with marked atrophy; high density of CD20<sup>+</sup> cells; low density of NK, TCD4<sup>+</sup> and active caspase-3 positive cells and strong expression of IL-10; leptospirosis patients had higher S100 and TNF-α positive cells in the spleen than the other groups.
|
31114579 |
2019 |
|
Leprosy
|
0.010 |
Biomarker
|
disease |
BEFREE |
(i) In demonstrating neural granuloma, sensitivity of H and E was 48.27% and that of S100 was 100%, (ii) Morphology of nerve fragments on S100 stain for cases of leprosy was fragmented and infiltrated in 37, intact and infiltrated in 19, reduced, fragmented, and infiltrated in seven, and absent in one, (iii) There was a significant difference (<i>P</i> <0.001) in the pattern of staining of S100 on intact nerve and nerves involved by granuloma in leprosy, and (iv) The probability to differentiate between leprosy and nonleprosy granuloma was statistically significant (<i>P</i> <0.001).
|
29937557 |
2019 |
|
Human immunodeficiency virus (HIV) II infection category B1
|
0.100 |
Biomarker
|
disease |
BEFREE |
Human immunodeficiency virus type 1 Nef protein mediates neural cell death: a neurotoxic role for IP-10.
|
15518810 |
2004 |
|
Non-Neoplastic Disorder
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Non-neoplastic glands also frequently expressed S100 A2 diminishing its potential diagnostic utility.
|
18223320 |
2008 |
|
Clear Cell Sarcoma of Soft Tissue
|
0.030 |
Biomarker
|
disease |
BEFREE |
Clear cell sarcomas and melanomas were also examined for their immunoreactivity to S-100 protein and HMB-45 antigen.
|
2004337 |
1991 |
|
Histiocytosis with joint contractures and sensorineural deafness
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
SHML cells expressed the following: (1) S-100 protein, (2) "pan-macrophage" antigens such as EBM11, HAM 56, and Leu-M3, (3) antigens functionally associated with phagocytosis (Fc receptor for IgG, complement receptor 3), and lysosomal activity (lysozyme, alpha 1-antichymotrypsin, and alpha 1-antitrypsyn), (4) antigens associated with early inflammation (Mac-387, 27E10), (5) antigens commonly found on monocytes, but not tissue macrophages (OKM5, Leu-M1), and (6) "activation" antigens (Ki-1 and receptors for transferrin and interleukin 2).
|
2180014 |
1990 |
|
Secondary malignant neoplasm of liver
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Liver metastasis was significantly correlated with overexpression of S100B (p=0.001, OR=9.217), TM4SF3 (p=0.011, OR=4.385), and OLFM4 (p=0.015, OR=3.438).
|
22011044 |
2012 |
|
Adenosis of Breast
|
0.020 |
Biomarker
|
disease |
BEFREE |
Microglandular adenosis (MGA) is a rare proliferative lesion of the breast composed of small glands lacking myoepithelial cells and lined by S100-positive, oestrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative epithelial cells.
|
26806567 |
2016 |
|
Human immunodeficiency virus (HIV) II infection category B1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Human Immunodeficiency Virus-1 (HIV-1) encodes a 27 kDa Negative Factor or Nef protein, which is increasingly proving to be a misnomer.
|
26915805 |
2016 |
|
Human immunodeficiency virus (HIV) II infection category B1
|
0.100 |
Biomarker
|
disease |
BEFREE |
Human immunodeficiency virus (HIV)-negative factor (Nef) protein is an accessory pathogenic factor, which plays a significant role in acquired immune deficiency syndrome (AIDS).
|
27981421 |
2017 |
|
Indeterminate dendritic cell tumor
|
0.020 |
Biomarker
|
disease |
BEFREE |
Indeterminate dendritic cell tumor (IDCT) is a proliferation of CD1a+, S100+ and langerin- histiocytes with a generally benign course.
|
28966519 |
2017 |
|
Cellular neurothekeoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Cellular neurothekeoma (CNT) is a dermal lesion with still unknown histogenesis, characterized by immunohistochemical staining for NKI/C3, NSE, MiTF, CD10 and CD68, whereas S100 protein, desmin and cytokeratins are negative.
|
30311258 |
2019 |
|
Sinus histiocytosis
|
0.070 |
AlteredExpression
|
disease |
BEFREE |
Rosai-Dorfman disease (RDD) is an enigmatic histiocytic disorder classically diagnosed by a distinctive combination of pathological features: emperipolesis, or migration of intact haematological cells through the voluminous cytoplasm of lesional histiocytes, and expression of S100 by these histiocytes.
|
31172509 |
2019 |
|
Sinus histiocytosis
|
0.070 |
Biomarker
|
disease |
BEFREE |
Rosai-Dorfman disease (RDD) is a rare entity characterized by proliferating S100-positive histiocytes.
|
31368911 |
2019 |
|
Sinus histiocytosis
|
0.070 |
Biomarker
|
disease |
BEFREE |
Rosai-Dorfman disease (RDD) is an uncommon disorder, characterized by an atypical expansion of histiocytes which classically shows emperipolesis and immunoreactivity with S-100 protein.
|
31436555 |
2019 |
|
Acidosis, Respiratory
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Respiratory acidosis is associated to high concentrations of S100B protein in umbilical cord blood at birth.
|
31473201 |
2019 |
|
Alzheimer's Disease
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
S100beta overexpression in Alzheimer's disease correlates with the proliferation of betaAPP-immunoreactive neurites in beta-amyloid plaques.
|
10617132 |
2000 |
|
Down Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
S-100 beta, a gene triplicated in Down Syndrome (DS), is thought to play a role in development of the brain in general, and in the serotonergic neuronal system in particular.
|
12742260 |
2003 |
|
Complete Trisomy 21 Syndrome
|
0.100 |
Biomarker
|
disease |
BEFREE |
S-100 beta, a gene triplicated in Down Syndrome (DS), is thought to play a role in development of the brain in general, and in the serotonergic neuronal system in particular.
|
12742260 |
2003 |
|
melanoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
S100 calcium-binding proteins such as S100B are elevated in primary malignant melanoma and are used as markers for this and numerous other cancers.
|
15178678 |
2004 |
|
Immunologic Deficiency Syndromes
|
0.100 |
Biomarker
|
group |
BEFREE |
Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors.
|
15194762 |
2004 |