|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Greater tumor thickness was observed in 25 lesions (69.4%) with S-100, 20 lesions (55.5%) with Melan-A and 17 (47.2%) lesions in HMB-45 rather than H&E staining.
|
30875030 |
2019 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
This results in a deregulated expression of some S100 genes associated with neoplasias.
|
11991838 |
2002 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The system uses S100 to define pixels as melanoma (tumor mask) within the array spot and measures intensity of TRAIL-receptor expression using Cy5-conjugated antibodies within the mask.
|
16778114 |
2006 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Furthermore, in vivo experiments have proven the role of S100 proteins in tumour growth and disease progression, while other studies have shown their prognostic value and involvement in resistance to chemotherapy drugs.
|
25880590 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
We used comprehensive histologic subtyping to provide a semiquantitive assessment of histologic patterns in each tumor and performed immunohistochemical analyses including S100/vimentin/mammaglobin/DOG1.
|
25976476 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Immunoreactivity for CD34, h-caldesmon, alpha-smooth-muscle actin (SMA), desmin, and S-100 was observed in 156 (91.2%), 131 (76.6%), 46 (26.9%), 7 (4.1%), and 14 (8.2%) tumors, respectively.
|
12152168 |
2002 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
On IHC, the tumor cells were focally positive for S-100 protein and α-smooth muscle actin; nuclear β-catenin expression was also seen.
|
30592181 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Immunohistochemically, the tumor cells were positive for melanosome (HMB45), S100 protein, KIT and Platelet derived growth factor receptor-alpha (PDGFRA).
|
19496203 |
2009 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The S100 calcium-binding protein family are inflammatory molecules that contribute to the development of a pro-inflammatory tumor microenvironment.
|
29345293 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The lesions stained positively for S-100 protein and a marker antigen for the mutated transgenic NF2 protein, confirming that the imaged tumors and areas of hyperplasia were of Schwann cell origin and expressed the mutated NF2 protein.
|
12407444 |
2003 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
However, few S-100 positive lipoblasts suggested the origin of the tumor.
|
31796335 |
2020 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Immunohistochemistry, performed in four cases, revealed positivity for S-100 and pancytokeratin in two of three neoplasms stained for each marker.
|
23672313 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Some of the cells belonging to the solid, proliferative areas, some of the abluminal cells, that are part of the proliferative ductal units and certain myxoid stellate or plasmocytoid cells contain the S100 protein, which would indicate the existence of some processes of mesenchymal epithelial÷myoepithelial transdifferentiation in the development of this type of salivary tumor.
|
28523310 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
This Review highlights new findings regarding the role of S100 family members in cancer diagnosis and treatment, the contribution of S100 signalling to tumour biology, and the discovery and development of S100 inhibitors for treating cancer.
|
25614008 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Expression of hnRNP A2/B1, hnRNP B1 and S100 A2 was increased in the tumor group when compared with the microscopic tumor-free specimens in 10% versus 5% (n.s.), 91% versus 5% and 65% versus 6%, respectively.
|
17067748 |
2006 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Immunostaining revealed that the tumors were positive for S-100 protein and vimentin and negative for glial fibrillary acidic protein, actin, and keratin.
|
2305928 |
1990 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
KIT was immunohistochemically detected in 98%, CD34 in 40%, smooth muscle actin in 34%, desmin in 0.2%, and S-100 protein in 14% of the tumors tested.
|
16625094 |
2006 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The immunohistochemical reactivity for epithelial membrane antigen, the lack of reactivity for S-100 protein, and the presence of ultrastructural features of perineurial cells are typical of this tumor.
|
9042282 |
1997 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Immunohistochemically, the tumour cells were positive for S100 protein.
|
9568513 |
1998 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Dermal non-neural granular cell tumor (NNGCT) was first described in 1991 as an S100-negative polypoid non-melanocytic tumor.
|
28266050 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The percentages of tumors staining positively were as follows: micro-ophthalmia-associated transcription factor, NKI/C3, bcl-1, E-cadherin, and cathepsin K (100%); HMB-45, 4E-binding protein 1, and CD68 (88%); smooth muscle actin and muscle-specific actin (40%); S100 (38%); calponin (20%); desmin (13%); and melan-A, SOX10, and keratin (0%).
|
25267378 |
2014 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
NEF is a tumor suppressing long non-coding (lnc)RNA in hepatocellular carcinoma.
|
31258706 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Neuropathological studies, assayed by immunohistochemical staining, showed that the tumor sample was positive to antibodies against S-100, CgA, AE1/AE3 (cytokeratin), Ki-67, INI1 and TP53, and was negative to antibodies against Nestin, GFAP, CD133, EMA and AFP.
|
22534715 |
2012 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Baseline tumor markers (LDH, S100B), baseline CT imaging biomarkers (tumor burden, Choi density) and CT texture parameters (Entropy, Kurtosis, Skewness, uniformity, MPP, UPP) of the largest target lesion were extracted.
|
31704599 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Three tumors were immunoreactive for S100 protein.
|
27816723 |
2017 |