SCT, secretin, 6343

N. diseases: 230; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026857
Disease: Musculoskeletal Diseases
Musculoskeletal Diseases
0.010 Biomarker group BEFREE The purpose of this study was to identify and quantify the misinformation present in online direct-to-consumer (DTC) advertising of SCT targeting patients with musculoskeletal disease in the U.S. 31770294 2020
CUI: C0677898
Disease: invasive cancer
invasive cancer
0.010 Biomarker phenotype BEFREE We obtained pancreatic juice samples from 38 patients (35 with biopsy-proven PDAC or pancreatic cystic lesions with invasive cancer and 3 with HGD) and 73 controls (32 with normal pancreas and 41 with benign disease), collected endoscopically from the duodenum after secretin administration from February 2015 through November 2016 at 3 medical centers. 31323382 2020
CUI: C0000735
Disease: Abdominal Neoplasms
Abdominal Neoplasms
0.010 Biomarker group BEFREE The purpose of this study was to develop a method enabling synthetic computed tomography (sCT) generation of the whole abdomen using magnetic resonance imaging (MRI) scans of pediatric patients with abdominal tumors. 30669135 2019
CUI: C0005940
Disease: Bone Diseases
Bone Diseases
0.010 Biomarker group BEFREE To date, 92 receptors (5 glutamate family, 67 rhodopsin family, 5 adhesion, 4 frizzled/taste2 family, 5 secretin family, and 6 other 7TM receptors) have been associated with bone diseases and dysfunctions (36 in humans and 72 in animals). 31646011 2019
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression disease BEFREE Herein, we studied the role of PROX1 in angiogenesis in cell lines derived from follicular thyroid cancer (FTC: FTC-133) and squamous cell carcinoma of the thyroid gland (SCT: CGTH-W-1) upon <i>PROX1</i> knockdown. 31717665 2019
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.010 Biomarker group BEFREE Taken together, we comprehensively demonstrated the critical role of SCT in the cardiovascular and pulmonary systems and provide new insight into the potential role of SCT in the pathological development of cardiopulmonary and cardiovascular diseases. 31578376 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.010 Biomarker disease BEFREE For example, serum SCT in patients with congestive heart failure was one-third of the normal level. 31578376 2019
CUI: C0029453
Disease: Osteopenia
Osteopenia
0.010 GeneticVariation disease BEFREE Bone loss and endocrine dysfunction are potential late complications of allogeneic stem cell transplant (allo-SCT); however, scant information concerning the long-term effects in SCT adult patients is available. 31650625 2019
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.010 Biomarker disease BEFREE Small airway remodelling and pulmonary inflammation were also found in SCT<sup>-/-</sup> mice. 31578376 2019
CUI: C0034372
Disease: Quadriplegia
Quadriplegia
0.010 Biomarker disease BEFREE Although SCT appears as a promising method for the treatment of neurological conditions, e.g., complete tetraplegia, much work should be done towards the development of rehabilitation protocols. 30931325 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.010 Biomarker group BEFREE Additionally, since there is still not enough convincing evidence about the effect of SCT on humans, e.g., in stroke, there have been no studies conducted concerning rehabilitation program formation and expected outcomes. 30931325 2019
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma
0.010 Biomarker disease BEFREE Consecutive patients (age ≥16 years) having B and T cell lymphoma who underwent SCT and who had PET/CT scan pre-SCT and 3 months post SCT were included in the study. 30583985 2019
CUI: C0079774
Disease: Peripheral T-Cell Lymphoma
Peripheral T-Cell Lymphoma
0.010 Biomarker disease BEFREE We confirm the 5-year OS of around 50% in PTLs undergoing auto-SCT. 31065733 2019
Ki-1+ Anaplastic Large Cell Lymphoma
0.010 Biomarker disease BEFREE This result suggests that allo-SCT using the RIC regimen may be effective for relapsed or refractory ALCL in children, adolescents, and young adults, even in non-CR cases. 31620968 2019
CUI: C0206682
Disease: Follicular thyroid carcinoma
Follicular thyroid carcinoma
0.010 Biomarker disease BEFREE Herein, we studied the role of PROX1 in angiogenesis in cell lines derived from follicular thyroid cancer (FTC: FTC-133) and squamous cell carcinoma of the thyroid gland (SCT: CGTH-W-1) upon <i>PROX1</i> knockdown. 31717665 2019
CUI: C0278695
Disease: Neuroblastoma recurrent
Neuroblastoma recurrent
0.010 Biomarker disease BEFREE NKI following haplo-SCT was relatively safe and feasible in patients with recurrent neuroblastoma. 31834883 2019
CUI: C0282193
Disease: Iron Overload
Iron Overload
0.010 Biomarker disease BEFREE Thus, SF is not reliable for iron overload diagnosis after SCT in every condition. 31535426 2019
CUI: C1853926
Disease: NONAKA MYOPATHY
NONAKA MYOPATHY
0.010 GeneticVariation disease BEFREE Bath application of secretin (100 nM) significantly increased the frequency of the spontaneous postsynaptic currents (sPSCs) to 118.0 ± 2.64% compared to the control, and that of the GABAergic miniature postsynaptic currents (mPSCs) to 147.6 ± 19.19%. 31507377 2019
CUI: C2931367
Disease: Thyroid cancer, follicular
Thyroid cancer, follicular
0.010 Biomarker disease BEFREE Herein, we studied the role of PROX1 in angiogenesis in cell lines derived from follicular thyroid cancer (FTC: FTC-133) and squamous cell carcinoma of the thyroid gland (SCT: CGTH-W-1) upon <i>PROX1</i> knockdown. 31717665 2019
CUI: C3714636
Disease: Pneumonitis
Pneumonitis
0.010 Biomarker disease BEFREE Small airway remodelling and pulmonary inflammation were also found in SCT<sup>-/-</sup> mice. 31578376 2019
CUI: C4049328
Disease: Renal medullary carcinoma
Renal medullary carcinoma
0.010 Biomarker disease BEFREE The patient was not of African descent, and did not have SCT or any other hereditary blood abnormality typical of RMC. 31617267 2019
CUI: C4744720
Disease: High Risk Acute Myeloid Leukemia
High Risk Acute Myeloid Leukemia
0.010 Biomarker disease BEFREE To compare the safety and efficacy of prophylactic DLI for prevention of relapse after allogeneic peripheral blood stem cell transplantation from haploidentical donors (HID-SCT) and matched-sibling donors (MSD-SCT) in patients with very high-risk acute myeloid leukemia (AML), we performed a retrospective analysis in a cohort of 21 HID-SCT and 13 MSD-SCT recipients, displaying similar baseline characteristics except for donor's gender distribution. 30747249 2019
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis
0.010 Biomarker disease BEFREE The expression and activity of key inflammatory mediators and apoptosis were evaluated in the presence or absence of the atrial peptide, secretin or both in cerulein-induced acute pancreatitis in rats. 29117461 2018
CUI: C0002871
Disease: Anemia
Anemia
0.010 GeneticVariation disease BEFREE Co-inheritance of each additional copy of the -α3.7 deletion significantly lowered the risk of anemia and chronic kidney disease among individuals with SCT (P-interaction = 0.031 and 0.019, respectively). 29590102 2018
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 GeneticVariation disease BEFREE Three CP patients improved their cytogenetic response (CyR) to complete CyR (CCyR), two after SCT and one on omacetaxine. 28972430 2018