XYLT2, xylosyltransferase 2, 64132

N. diseases: 138; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024809
Disease: Marijuana Abuse
Marijuana Abuse
0.010 Biomarker disease BEFREE Prescribed treatment included 4 daily doses of 500 μg tetrahydrocannabinol each delivered from 16 mg cannabis flos per inhalation plus up to an additional four SOS (distress code for more doses of cannabis) doses.ResultDaily cannabis dose consumed during hospitalization with the Syqe Inhaler was 51 mg (20-96) versus 1,000 mg (660-3,300) consumed prehospitalization. 31196236 2020
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases
0.010 GeneticVariation group BEFREE Although all QUS parameters (SI, SOS and BUA) were associated with any or major fracture incidence in non-CKD and CKD patients, the magnitude of these associations was lower for any fracture and for BUA. 31676408 2020
CUI: C0023787
Disease: Lipodystrophy
Lipodystrophy
0.010 Biomarker disease BEFREE Adipose tissue loss and lipodystrophy in xylosyltransferase II deficient mice. 30778123 2019
CUI: C0023895
Disease: Liver diseases
Liver diseases
0.010 GeneticVariation group BEFREE An exploratory multivariate model identified a past history of liver disease and thrombocytopenia before conditioning therapy as dominant risk factors for SOS after transplant. 30120894 2019
CUI: C0040034
Disease: Thrombocytopenia
Thrombocytopenia
0.010 GeneticVariation phenotype BEFREE An exploratory multivariate model identified a past history of liver disease and thrombocytopenia before conditioning therapy as dominant risk factors for SOS after transplant. 30120894 2019
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.010 Biomarker group BEFREE Deletion of the Env cytoplasmic tail improved the efficiency with which the SOS Env supported virus infection in a reducing environment. 30944182 2019
CUI: C0162869
Disease: Aneurysm, Ruptured
Aneurysm, Ruptured
0.010 Biomarker disease BEFREE Patterns of care for ruptured aneurysms of the middle cerebral artery: analysis of a Swiss national database (Swiss SOS). 31731273 2019
CUI: C0432242
Disease: Desbuquois syndrome
Desbuquois syndrome
0.010 GeneticVariation disease BEFREE Biallelic variants in XYLT1 and XYLT2, encoding xylosyltransferases, are associated with Desbuquois dysplasia type 2 and spondylo-ocular syndrome, respectively. 31438591 2019
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
0.010 Biomarker phenotype BEFREE These data suggest that ADCs that do not target antigens present in the normal liver have a relatively low frequency of SOS, but a relatively high frequency of DILI. 30120894 2019
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections
0.010 Biomarker group BEFREE Our results corroborate the AcrAB-TolC efflux pump and the SOS response proteins, RecA and RecC, as potential targets for ciprofloxacin helper drugs in treatment of human bacterial infections caused by <i>E. coli</i> strains with intermediate sensitivity to ciprofloxacin. 30013537 2018
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.010 Biomarker disease BEFREE The Barrow Neurological Institute Grading Scale as a Predictor for Delayed Cerebral Ischemia and Outcome After Aneurysmal Subarachnoid Hemorrhage: Data From a Nationwide Patient Registry (Swiss SOS). 29351673 2018
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.010 Biomarker disease BEFREE Latent moderated structural equations demonstrated that the relationship between SOS-SC and depression is moderated by social support (Sample 2), further validating the SOS-SC. 29052030 2018
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.010 Biomarker disease BEFREE Latent moderated structural equations demonstrated that the relationship between SOS-SC and depression is moderated by social support (Sample 2), further validating the SOS-SC. 29052030 2018
CUI: C0019163
Disease: Hepatitis B
Hepatitis B
0.010 GeneticVariation disease BEFREE Awareness campaigns and voluntary hepatitis B screening were organized in the twelve districts of Ouagadougou by the "SOS Hepatitis Burkina" association. 30081915 2018
CUI: C0020433
Disease: Hyperbilirubinemia
Hyperbilirubinemia
0.010 Biomarker disease BEFREE Typical symptoms of VOD/SOS may include hyperbilirubinemia, painful hepatomegaly, weight gain, and ascites. 29945939 2018
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.010 GeneticVariation disease BEFREE Risk of acute myocardial infarction during use of individual NSAIDs: A nested case-control study from the SOS project. 30383755 2018
CUI: C0240066
Disease: Iron deficiency
Iron deficiency
0.010 Biomarker disease BEFREE These results showed that iron deficiency causes <i>C. crescentus</i> cells to suffer oxidative stress and to activate the SOS response, indicating an increase in DNA damage. 30210482 2018
CUI: C0342649
Disease: Vascular calcification
Vascular calcification
0.010 GeneticVariation phenotype BEFREE Qualitatively, most PDIP-SOS CMR images showed good-to-excellent confidence to detect vascular calcifications, with good-to-excellent inter-reader agreement (κ = 0.67 for ilio-femoral region, P < 0.001; κ = 0.80 for aorto-iliac region, P < 0.01). 30078377 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.010 Biomarker phenotype BEFREE Latent moderated structural equations demonstrated that the relationship between SOS-SC and depression is moderated by social support (Sample 2), further validating the SOS-SC. 29052030 2018
CUI: C0553580
Disease: Ewings sarcoma
Ewings sarcoma
0.010 Biomarker disease BEFREE This mono-institutional observational study was conducted to determine incidence, severity, risk factors, and outcome of sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) in high-risk Ewing sarcoma (ES) patients treated with intravenous busulfan and melphalan (BU-MEL) followed by autologous stem cell transplantation (ASCT). 29335623 2018
CUI: C0948441
Disease: Venoocclusive disease
Venoocclusive disease
0.010 GeneticVariation group BEFREE Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life-threatening complication that can develop after hematopoietic cell transplantation. 30076031 2018
Human immunodeficiency virus (HIV) II infection category B1
0.010 Biomarker disease BEFREE In this study, we examined the antibacterial effect of Tat (47-58) peptide, a cell-penetrating peptide, derived from human immunodeficiency virus-1 by focusing on the glutathione and SOS response. 30393132 2018
CUI: C0003872
Disease: Arthritis, Psoriatic
Arthritis, Psoriatic
0.010 GeneticVariation disease BEFREE This report includes 1,991 subjects who underwent bariatric surgery and 2,018 controls with obesity from the SOS study; none of them had psoriasis or PsA at baseline. 29178583 2017
CUI: C0023643
Disease: Lichen disease
Lichen disease
0.010 AlteredExpression disease BEFREE SOS response in bacteria: Inhibitory activity of lichen secondary metabolites against Escherichia coli RecA protein. 28515022 2017
CUI: C0026277
Disease: Mixed Salivary Gland Tumor
Mixed Salivary Gland Tumor
0.010 Biomarker disease BEFREE The relationship between proteoglycan inhibition via xylosyltransferase II silencing and the implantation of salivary pleomorphic adenoma. 27732748 2017