HNF1B, HNF1 homeobox B, 6928

N. diseases: 279; N. variants: 72
Disease: Prostate carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.200 GeneticVariation disease GWASCAT Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. 27197191 2016
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.200 GeneticVariation disease GWASCAT Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 29892016 2018
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.200 Biomarker disease BEFREE As in studies from other populations, our findings indicate that HNF1B is also associated with prostate cancer risk in the Korean population. 21982019 2011
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.200 AlteredExpression disease BEFREE Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer. 20569440 2010
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.200 GeneticVariation disease BEFREE A mediation analysis of 9,065 PCa cases and 9,526 controls failed to produce evidence that diabetes mediates the association of the HNF1B locus with PCa risk. 23193118 2012
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.200 GeneticVariation disease GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056 2015
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.200 GeneticVariation disease GWASCAT 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. 31562322 2019