|
Lymphoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
CD2+, CD3-, CD56/NCAM+ malignant lymphoma with TCR beta gene rearrangement: a case report.
|
7485082 |
1995 |
|
Lymphoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
CD43 antigen was positive, and rearrangement of TCR-beta gene was observed.The lymphoma was the T-cell type.
|
8127156 |
1994 |
|
Lymphoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Neither DNA flow cytometry nor TCR gene rearrangement can predict the 15% to 19% of patients in whom a lymphoma will develop.
|
8288780 |
1994 |
|
Lymphoma
|
0.100 |
Biomarker
|
group |
BEFREE |
DNA studies of the lymphoma at the first presentation demonstrated dual rearrangement in the T-cell receptor beta (TCR beta) and immunoglobulin heavy chain J region (IgJH) genes.
|
8299098 |
1994 |
|
Lymphoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
We describe three cases of immunodeficiency-associated lymphomas, two in patients with acquired immunodeficiency syndrome (AIDS) and one in a patient with a renal transplant, in which both immunoglobulin and TCR gene rearrangements were identified.
|
7943530 |
1994 |
|
Lymphoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
This prompted us to investigate lymphoma biopsies from 7 non-Oriental patients with NTCL for the expression of natural killer (NK) and T-cell antigens, including TCR proteins, for the presence of EBV-encoded latent membrane protein (LMP) using immunohistochemistry and for the presence of EBV DNA and Epstein-Barr early region (EBER) RNA using in situ hybridization (ISH).
|
8387835 |
1993 |
|
Lymphoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
We detected a 1.8 kb transcript homologous to human TEA that is spliced to C alpha in mouse thymic lymphomas showing concomitant rearrangement and expression of TCR gamma, delta, beta, and alpha.
|
8383995 |
1993 |
|
Lymphoma
|
0.100 |
Biomarker
|
group |
BEFREE |
We analyzed the organization of bcr, immunoglobulin and TCR genes in malignant lymphomas.
|
2160631 |
1990 |
|
Lymphoma
|
0.100 |
Biomarker
|
group |
BEFREE |
The remaining 67 lymphomas had a germline beta-chain TCR-gene configuration.
|
2157671 |
1990 |
|
Lymphoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
In conclusion, the Ig and TCR gene rearrangement pattern of the lymphomas found in Hong Kong correlates well with the T-cell and B-cell lineage, which is similar to reports in the white population.
|
2208029 |
1990 |
|
Lymphoma
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Nine patients had acute lymphoblastic leukaemia (T-ALL), nine patients had prolymphocytic leukaemia (PLL), six patients presented with a T-CLL/T-lymphocytosis syndrome, two patients had Sezary syndrome (SS) and one patient had HTLV-I positive T-cell leukaemia/lymphoma (ATLL). alpha TCR gene rearrangement could be demonstrated by the use of three available probes in only one case.
|
2961364 |
1987 |