TGFB1, transforming growth factor beta 1, 7040

N. diseases: 1558; N. variants: 50
Disease: Fibrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0016059
Disease: Fibrosis
Fibrosis 		0.600 Biomarker phenotype LHGDN Transforming growth factor-beta1 (TGF-beta1) is generally considered to be the major or predominant isoform involved in fibrosis, with the roles of TGF-beta2 and -beta3 being less clear. 12911534 2003
CUI: C0016059
Disease: Fibrosis
Fibrosis 		0.600 AlteredExpression phenotype LHGDN TGF-beta(1) expression was significantly correlated with both hepatic fibrosis and the percentage of portal tracts showing histological abnormalities associated with CFLD. 12000722 2002
CUI: C0016059
Disease: Fibrosis
Fibrosis 		0.600 Biomarker phenotype CTD_human In conclusion, this strongly suggests that TGF-beta1 derived from tubular epithelial cells and some macrophages might be related to the development of renal interstitial fibrosis in HgCl2-treated BN rats. 10469268 1999