TLR4, toll like receptor 4, 7099

N. diseases: 1174; N. variants: 54
Disease: Pneumonia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.400 Biomarker disease BEFREE Quite surprisingly, the absence of TLR4 greatly diminished pulmonary inflammation and the same phenotype was observed in PAFR-/- animals. 18292574 2008
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.400 Biomarker disease BEFREE A similar challenge with Hsp72 in TLR4 mutant mice did not stimulate the inflammatory response, stressing the importance of TLR4 in Hsp72-mediated lung inflammation. 17947709 2007
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.400 Biomarker disease BEFREE To determine the role of TLR4 in L. pneumophila pneumonia, C3H/HeJ mice, which display a nonfunctional gene encoding TLR4 (TLR4), and wild-type (wt) C3H/HeN mice were intranasally inoculated with L. pneumophila serogroup 1. 12195388 2002