Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Previous studies led to the isolation of two overlapping cDNA clones that encode polypeptides of TPO (85 residues, C2; 100 residues, C21) recognized by sera from several patients with autoimmune disease that contained antimicrosomal autoantibodies.
|
1716261 |
1991 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
In new-onset insulin-dependent diabetic patients the presence of anti-thyroid peroxidase antibodies is associated with islet cell autoimmunity and the high risk haplotype HLA DQA1*0301-DQB1*0302. Belgian Diabetes Registry.
|
8737022 |
1996 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Familial clustering of juvenile thyroid autoimmunity: higher risk is conferred by human leukocyte antigen DR3-DQ2 and thyroid peroxidase antibody status in fathers.
|
12161510 |
2002 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
In euthyroid individuals, autoantibodies to thyroid peroxidase (TPOab) and thyroglobulin (Tgab) are regarded as early markers of thyroid autoimmunity.
|
16381988 |
2006 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Using thyroid peroxidase autoantibodies (TPOAbs) as an indicator of thyroid autoimmunity, we assessed whether the association of these loci is different in type 1 diabetes patients with TPOAbs than in those without.
|
17334650 |
2007 |
Autoimmune Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
Hashimoto's thyroiditis, a common autoimmune disease, is associated with autoantibodies to thyroglobulin (Tg) and thyroid peroxidase (TPO).
|
20573721 |
2010 |
Autoimmune Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
Thyroid peroxidase (TPO) gene variations are one cause of thyroid autoimmune diseases.
|
22326521 |
2012 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Non-organ specific AAb (ANA, anti-Ro52, anti-Ro60, anti-La, anti-RNP) but not anti-thyroid peroxidase, anti-tissue transglutaminase or myositis-specific antibodies, were more frequent in s-IBM patients, and 14/51 (27%) had another autoimmune disease (Sjögren's syndrome, thyroiditis, psoriasis, vitiligo).
|
22554526 |
2012 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Serum immunoglobulin G antibodies against H pylori (enzyme-linked immunosorbent assay), CagA protein (Western blot assay), circulating antibodies to thyroid antigens, mainly thyroperoxidase (TPOAbs) and thyroglobulin (TgAbs), were tested in 101 females with HT and 111 non-HT control women without a history of autoimmune disease.
|
27442635 |
2016 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
CTD_human |
The Association of Serum Bisphenol A with Thyroid Autoimmunity.
|
27869686 |
2016 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
We have recently shown that thyroperoxidase antibody positivity impairs the thyroidal response to hCG stimulation, which may suggest that this is a mechanism through which thyroid autoimmunity acts as a risk factor for thyroid disease.
|
28049387 |
2017 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
The high prevalence of thyroid peroxidase antibodies (TPOAbs) in patients with breast cancer and their protective role had previously been demonstrated, indicating a link between breast cancer and thyroid autoimmunity.
|
28575127 |
2017 |
Autoimmune Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
We recently showed that thyroid autoimmunity severely attenuated the thyroidal response to hCG stimulation and that this may underlie the higher risk of premature delivery in thyroperoxidase antibody (TPOAb)-positive women.
|
28911134 |
2017 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Autoimmune diseases in the family increased the risk of thyroid autoimmunity: TPOAb (OR: 2.2, <i>p</i> = 0.012), any autoantibody (OR: 1.7, <i>p</i> = 0.04), and both autoantibodies (OR: 2.2, <i>p</i> = 0.024).
|
29234623 |
2017 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Autoimmune thyroid disease (AITD), which is characterized by an increased presence of thyroid autoantibodies (TAbs), such as antibodies against thyroid peroxidase (TPOAbs) and antibodies against thyroglobulin (TgAbs), has been reported to be associated with rheumatoid arthritis (RA) because AITD and RA both involve autoimmunity.
|
29312834 |
2018 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
<sup>131</sup>I-IGD was more common in patients with pre-treatment direct or indirect signs of autoimmunity: positive anti-TPO (p < 0.05), glandular hypoechogenicity, TRAbs within reference range, diffuse uptake on 99mTc-pertechnetate scans (p < 0.05), findings that may increase the risk tenfold.
|
29353393 |
2018 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Thyroid autoimmunity was assessed with antibodies against thyroid peroxidase (TPOAb).
|
29373441 |
2018 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Autoantobodies (AAbs) to thyroid peroxidase (anti-TPO) and thyroglobulin (anti-Tg) as well as AAbs to transglutaminase 2 (anti-TG2) and antibodies to gliadins (anti-gliadins) are serological markers of autoimmune thyroid disease and celiac disease, respectively, and players in pathogenesis of these autoimmune diseases.
|
29422338 |
2018 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Females were at higher risk of multiple autoimmunity; TGA/CD were associated with younger age and TPOA with older age.
|
29431870 |
2018 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Although numerous papers demonstrated the significant increase in the prevalence of thyroid autoimmunity (positive intrathyroidal lymphocyte infiltration and/or anti-thyroglobulin/thyroid peroxidase antibodies) in patients with thyroid cancers as compared to those with benign nodules, and also the significant increase in the prevalence of papillary thyroid cancer (PTC) in patients with thyroid autoimmunity as compared to those without, there are some crucial biases that should be taken into account for their interpretation.
|
30081426 |
2018 |
Autoimmune Diseases
|
0.500 |
AlteredExpression
|
group |
BEFREE |
The prevalence of thyroid autoimmunity was 6.9%, overrepresented in girls (p < .001) also having higher TPOAb levels at 10 years (p = .049).
|
30486698 |
2018 |
Autoimmune Diseases
|
0.500 |
GeneticVariation
|
group |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Autoimmune Diseases
|
0.500 |
GeneticVariation
|
group |
BEFREE |
However, the subset of hypothyroidism single-nucleotide polymorphisms involved in autoimmunity and thyroid peroxidase antibodies levels were not associated with AF.
|
30673084 |
2019 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
Autoimmunity to TPO is characterised by autoantibodies and T cell reactivity in Hashimoto's disease and Graves' disease.
|
30742860 |
2019 |
Autoimmune Diseases
|
0.500 |
Biomarker
|
group |
BEFREE |
The following terms were used for the search: [subclinical hypothyroidism OR thyroid autoimmunity OR thyroperoxidase antibody (TPO-Ab) OR thyroglobulin antibodies (Tg-Ab)] AND (levothyroxine OR euthyrox) AND [pregnancy outcome OR miscarriage OR abortion OR pregnancy loss OR preterm birth OR premature delivery OR early labo(u)r].
|
30951172 |
2019 |