Complement Component 7 Deficiency
|
0.720 |
Biomarker
|
disease |
BEFREE |
The relatives (parents and one sister) had half-normal levels of both immunochemically and functionally determined C7, indicating a heterozygous state for C7 deficiency.
|
2792129 |
1989 |
Complement Component 7 Deficiency
|
0.720 |
Biomarker
|
disease |
BEFREE |
Hereditary complement C7 deficiency in nine families: subtotal C7 deficiency revisited.
|
17407100 |
2007 |
Complement deficiency disease
|
0.420 |
Biomarker
|
group |
BEFREE |
A novel screening assay was used to investigate for terminal complement deficiency and the 2 affected brothers were found to be completely deficient in the seventh component of complement (C7).
|
7523157 |
1994 |
Complement deficiency disease
|
0.420 |
Biomarker
|
group |
BEFREE |
In addition, the simultaneous occurrence of two hereditary complement deficiencies (C2 and C7) was discovered in one family of this remarkable kindred.
|
409732 |
1977 |
Meningococcal Infections
|
0.040 |
Biomarker
|
group |
BEFREE |
Complement C7 deficiency is associated with increased susceptibility to meningococcal infection.
|
16552475 |
2006 |
Meningococcal Infections
|
0.040 |
Biomarker
|
group |
BEFREE |
We report the recurrence of fulminant meningococcal disease in a complement component C7-deficient patient.
|
15889368 |
2005 |
Meningococcal Infections
|
0.040 |
Biomarker
|
group |
BEFREE |
We report studies of an Irish family in which the index case had suffered recurrent meningococcal disease and was found to be deficient in the seventh component of complement (C7).
|
9844043 |
1998 |
Meningococcal Infections
|
0.040 |
Biomarker
|
group |
BEFREE |
An apparently completely complement C7-deficient patient with refractory otitis media and two episodes of meningococcal disease was given therapeutic plasma transfusions in 1992 and 1994.
|
8774358 |
1996 |
Arthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Complete absence of C7 was also found in one sibling who had the clinical syndrome of meningococcal meningitis and arthritis as a child and in this sibling's clinically well eight-year-old son.
|
100562 |
1978 |
Meningococcal meningitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Complete absence of C7 was also found in one sibling who had the clinical syndrome of meningococcal meningitis and arthritis as a child and in this sibling's clinically well eight-year-old son.
|
100562 |
1978 |
Otitis Media
|
0.010 |
Biomarker
|
disease |
BEFREE |
An apparently completely complement C7-deficient patient with refractory otitis media and two episodes of meningococcal disease was given therapeutic plasma transfusions in 1992 and 1994.
|
8774358 |
1996 |
Recurrent meningitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
We describe an 11-year-old girl suffering from recurrent meningitis with a complete absence of the seventh component of complement (C7).
|
2792129 |
1989 |
Familial (FPAH)
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
DNA polymorphism of the human complement component C7 gene in familial deficiencies.
|
1973405 |
1990 |
Infectious Otitis Media
|
0.010 |
Biomarker
|
disease |
BEFREE |
An apparently completely complement C7-deficient patient with refractory otitis media and two episodes of meningococcal disease was given therapeutic plasma transfusions in 1992 and 1994.
|
8774358 |
1996 |
Complement Component 7 Deficiency
|
0.720 |
CausalMutation
|
disease |
CLINVAR |
Two novel mutations in the C7 gene in a Korean patient with complement C7 deficiency.
|
15831990 |
2005 |
C7 AND C6 DEFICIENCY, COMBINED SUBTOTAL
|
0.100 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
Complement Component 7 Deficiency
|
0.720 |
Biomarker
|
disease |
CTD_human |
|
|
|
Liver Cirrhosis, Experimental
|
0.300 |
Biomarker
|
disease |
CTD_human |
Systems level analysis and identification of pathways and networks associated with liver fibrosis.
|
25380136 |
2014 |
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
Complement deficiency disease
|
0.420 |
Biomarker
|
group |
HPO |
|
|
|
Recurrent meningococcal disease
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Membranous glomerulonephritis
|
0.200 |
Biomarker
|
disease |
RGD |
Detection of terminal complement components in experimental immune glomerular injury.
|
6241952 |
1984 |
Myocardial Infarction
|
0.200 |
Biomarker
|
disease |
RGD |
Time course studies on the initiation of complement activation in acute myocardial infarction induced by coronary artery ligation in rats.
|
15724448 |
2005 |
Visual seizure
|
0.200 |
Biomarker
|
disease |
RGD |
Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration.
|
12574424 |
2003 |