DHX40, DEAH-box helicase 40, 79665

N. diseases: 64; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0362046
Disease: Prediabetes syndrome
Prediabetes syndrome
0.010 Biomarker disease BEFREE ANOVA for PAD and diabetes subgroups showed a linear increase with disease burden with the highest difference between Fontaine I-NGT and Fontaine II-DGT (4.59 ± 0.40, 4.79 ± 0.43, p = 0.015). 31227875 2020
CUI: C0002871
Disease: Anemia
Anemia
0.010 Biomarker disease BEFREE Significant demographic and clinical determinants of anemia were ulcer duration more than one month prior to hospitalization (p<0.009), PAD (p<0.001) and presence of gangrene (p<0.001). 31846473 2019
CUI: C0008031
Disease: Chest Pain
Chest Pain
0.010 GeneticVariation phenotype BEFREE On the same µPAD platform, detection of prolonged elevation of levels of cTnT and CK-MB, which are only produced 6 h after the onset of chest pain in human serum, was possible. 30685097 2019
CUI: C0008055
Disease: Chikungunya Fever
Chikungunya Fever
0.010 Biomarker disease BEFREE The PAD could help health workers in the early diagnosis of tropical diseases such as CHIK, which require specific management protocols in at-risk populations. 30734316 2019
CUI: C0014556
Disease: Epilepsy, Temporal Lobe
Epilepsy, Temporal Lobe
0.010 Biomarker disease BEFREE TLE with hippocampal sclerosis presented a significantly higher brain-PAD than several other categories. 31160692 2019
CUI: C0017086
Disease: Gangrene
Gangrene
0.010 Biomarker disease BEFREE Significant demographic and clinical determinants of anemia were ulcer duration more than one month prior to hospitalization (p<0.009), PAD (p<0.001) and presence of gangrene (p<0.001). 31846473 2019
CUI: C0030193
Disease: Pain
Pain
0.010 GeneticVariation phenotype BEFREE Analyses of covariances and Pearson/Spearman correlations were used to determine associations of brain-PAD with pain, somatosensory function, and psychological function. 31009418 2019
CUI: C0032897
Disease: Prader-Willi Syndrome
Prader-Willi Syndrome
0.010 Biomarker disease BEFREE In the PWS group, brain-PAD scores were not associated with intelligence quotient (IQ), use of hormonal and psychotropic medications, nor severity of repetitive or disruptive behaviours. 30658944 2019
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.010 Biomarker group BEFREE The PAD showed few cross-reactions with other tropical viral diseases. 30734316 2019
CUI: C0085159
Disease: Seasonal Affective Disorder
Seasonal Affective Disorder
0.010 Biomarker disease BEFREE Interestingly, total T-cell proliferation was reduced post-IRT in both PAD and SAD patients, although the reduction in proliferation was primarily due to reduced CD4 T-cell proliferation in PAD (p = 0.025) in contrast to CD8 T-cells in SAD (p = 0.042). 31613907 2019
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.010 Biomarker disease BEFREE To overcome this limitation, a sensitive and rapid microfluidic paper-based device (µPAD) was developed for the simultaneous detection of multiple cardiac biomarkers for the early and late diagnosis of AMI. 30685097 2019
CUI: C0270853
Disease: Juvenile Myoclonic Epilepsy
Juvenile Myoclonic Epilepsy
0.010 Biomarker disease BEFREE PME had a higher brain-PAD than JME (22.0 vs. 9.3 years). 31160692 2019
Amputated structure (morphologic abnormality)
0.010 Biomarker phenotype BEFREE This population based national study aimed to determine outcomes following revascularisation for PAD and to identify predictors of major amputation after revascularisation, including geographical variation. 30293885 2019
CUI: C0597744
Disease: Secondary antibody deficiency
Secondary antibody deficiency
0.010 GeneticVariation disease BEFREE Patients with primary or secondary antibody deficiency (PAD or SAD) are at increased risk of recurrent infections that can be alleviated by immunoglobulin replacement therapy (IRT). 31613907 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome
0.010 Biomarker disease BEFREE Patients with acute coronary syndrome (ACS) and previous cardiovascular disease (CVD) (stroke, peripheral arterial disease [PAD] or coronary artery disease [CAD]) are at high risk of serious events and mortality. 31081301 2019
CUI: C0751785
Disease: Unverricht-Lundborg Syndrome
Unverricht-Lundborg Syndrome
0.010 Biomarker disease BEFREE PME had a higher brain-PAD than JME (22.0 vs. 9.3 years). 31160692 2019
CUI: C0852949
Disease: Arteriopathic disease
Arteriopathic disease
0.010 Biomarker group BEFREE Superficial femoral and popliteal artery disease are commonly involved in the development of symptomatic PAD. 30994309 2019
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.010 Biomarker disease BEFREE Patients with acute coronary syndrome (ACS) and previous cardiovascular disease (CVD) (stroke, peripheral arterial disease [PAD] or coronary artery disease [CAD]) are at high risk of serious events and mortality. 31081301 2019
CUI: C1504404
Disease: Hippocampal sclerosis
Hippocampal sclerosis
0.010 Biomarker disease BEFREE TLE with hippocampal sclerosis presented a significantly higher brain-PAD than several other categories. 31160692 2019
CUI: C3275069
Disease: Chronic Total Occlusion Vessel
Chronic Total Occlusion Vessel
0.010 Biomarker disease BEFREE In the DISRUPT PAD clinical trials, excellent acute results were obtained in moderate to severely calcified femoro-popliteal lesions, including a group of patients with CTOs. 30411605 2019
CUI: C0007282
Disease: Carotid Stenosis
Carotid Stenosis
0.010 Biomarker disease BEFREE Adjusted least squares mean psoas diameter estimates were 25.5 ± 1.1 cm<sup>2</sup> for participants with AAA, 26.7 ± 2.0 cm<sup>2</sup> for participants with carotid stenosis, and 22.7 ± 0.8 cm<sup>2</sup> for participants with PAD (P = .053 for PAD vs AAA; P = .057 for PAD vs carotid stenosis; and P = .564 for AAA vs carotid stenosis). 29276105 2018
CUI: C0011311
Disease: Dengue Fever
Dengue Fever
0.010 Biomarker disease BEFREE The PAD appears to have all the potential to assist health workers in early diagnosis of dengue fever or other tropical fevers caused by flaviviruses. 29525973 2018
CUI: C0035078
Disease: Kidney Failure
Kidney Failure
0.010 Biomarker disease BEFREE This study suggested early renal insufficiency is tightly linked to region-specific vascular stiffness and PAD. 29749701 2018
Malignant mesothelioma of pericardium
0.010 AlteredExpression disease BEFREE Citrullination-associated phenomena and PAD levels were found to be elevated in nanomaterials -treated cell lines as well as in the spleen, kidneys and lymph nodes of mice, suggesting a systemic response to nanomaterials injection, and validated in human pleural and pericardial malignant mesothelioma (MM) samples. 29330439 2018
CUI: C1285498
Disease: Vegetation
Vegetation
0.010 GeneticVariation disease BEFREE We compare prevalence (i.e., the proportion of individuals infested by chigger mites) and intensity (i.e., the average number of larvae and larvae clusters in infested individuals) at forest edge (<100 m) and interior (>100 m) from PAD A because variations in biotic (e.g., vegetation cover) and abiotic (e.g., relative humidity and temperature) factors are expected to influence chigger mite abundance. 29420130 2018