|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>Conclusions:</b> B7-H3 is a promising target for both vascular and epithelial sPA imaging of breast cancer.
|
28529630 |
2017 |
|
Breast Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>Conclusions:</b> B7-H3 is a promising target for both vascular and epithelial sPA imaging of breast cancer.
|
28529630 |
2017 |
|
Malignant Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
<b>Results:</b> B7-H3 expression was found positively correlated with the grade of malignancy, which might be caused by hypomethylation.
|
30377558 |
2018 |
|
Primary malignant neoplasm
|
0.100 |
AlteredExpression
|
group |
BEFREE |
<b>Results:</b> B7-H3 expression was found positively correlated with the grade of malignancy, which might be caused by hypomethylation.
|
30377558 |
2018 |
|
Malignant Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
<b>Results:</b> Immunostaining showed differential B7-H3 expression on both the endothelium and tumor epithelium in human breast cancer with an area under the ROC curve of 0.93 to differentiate breast cancer vs non-cancer.
|
28529630 |
2017 |
|
Primary malignant neoplasm
|
0.100 |
AlteredExpression
|
group |
BEFREE |
<b>Results:</b> Immunostaining showed differential B7-H3 expression on both the endothelium and tumor epithelium in human breast cancer with an area under the ROC curve of 0.93 to differentiate breast cancer vs non-cancer.
|
28529630 |
2017 |
|
Colon Carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
<i>In vivo</i> biodistribution and imaging studies were performed with positron emission tomography and magnetic resonance imaging (PET/MRI) studies to identify and quantitate <sup>89</sup>Zr-DS-5573a tumor uptake in a B7-H3-positive breast cancer model (MDA-MB-231) and a B7-H3-negative murine colon cancer model (CT26).
|
30128047 |
2018 |
|
Malignant tumor of colon
|
0.040 |
Biomarker
|
disease |
BEFREE |
<i>In vivo</i> biodistribution and imaging studies were performed with positron emission tomography and magnetic resonance imaging (PET/MRI) studies to identify and quantitate <sup>89</sup>Zr-DS-5573a tumor uptake in a B7-H3-positive breast cancer model (MDA-MB-231) and a B7-H3-negative murine colon cancer model (CT26).
|
30128047 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
<i>In vivo</i> biodistribution studies showed high uptake of <sup>89</sup>Zr-DS-5573a in B7-H3-expressing MDA-MB-231 tumor-bearing mice, achieving 32.32 ± 6.55 %ID/g on day 7 post injection in BALB/c <i>nu</i>/<i>nu</i> mice and 25.76 ± 1.79 %ID/g in SCID mice, with minimal evidence of non-specific uptake in normal tissues, and excellent tumor localization on PET/MRI.
|
30128047 |
2018 |
|
Osteosarcoma
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
4 studies investigated B7-H3 expression in osteosarcoma, but there is no study on B7-H3 expression in chondrosarcoma.
|
31060912 |
2019 |
|
Osteosarcoma of bone
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
4 studies investigated B7-H3 expression in osteosarcoma, but there is no study on B7-H3 expression in chondrosarcoma.
|
31060912 |
2019 |
|
Childhood Osteosarcoma
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
4 studies investigated B7-H3 expression in osteosarcoma, but there is no study on B7-H3 expression in chondrosarcoma.
|
31060912 |
2019 |
|
Chondrosarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
4 studies investigated B7-H3 expression in osteosarcoma, but there is no study on B7-H3 expression in chondrosarcoma.
|
31060912 |
2019 |
|
Malignant Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Cancer cell-expressed B7-H3 regulates the differentiation of tumor-associated macrophages in human colorectal carcinoma.
|
29113264 |
2017 |
|
Primary malignant neoplasm
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Cancer cell-expressed B7-H3 regulates the differentiation of tumor-associated macrophages in human colorectal carcinoma.
|
29113264 |
2017 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Tumor B7-H3 expression was significantly higher in immunocompetent vs. immunosuppressed patients, largely driven by very low expression in HIV+ patients.
|
29484464 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Tumor cell B7-H3 expression was associated with increased disease-specific mortality in high FOXP3+ cell number group (hazard ratio [HR] =2.98; <i>P</i>=0.017), but not in low FOXP3+ group (<i>P</i>=0.71).
|
31440091 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
B7-H3 blockade promoted CD8(+) T-cell infiltration into the tumour and induced a substantial anti-tumour effect on murine pancreatic cancer.
|
19844235 |
2009 |
|
Pancreatic carcinoma
|
0.060 |
Biomarker
|
disease |
BEFREE |
B7-H3 blockade promoted CD8(+) T-cell infiltration into the tumour and induced a substantial anti-tumour effect on murine pancreatic cancer.
|
19844235 |
2009 |
|
Malignant neoplasm of pancreas
|
0.050 |
Biomarker
|
disease |
BEFREE |
B7-H3 blockade promoted CD8(+) T-cell infiltration into the tumour and induced a substantial anti-tumour effect on murine pancreatic cancer.
|
19844235 |
2009 |
|
Pancreatic carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
B7-H3 expression was evaluated by immunohistochemistry in 68 patients with pancreatic cancer who underwent surgical tumor resection.
|
20035626 |
2009 |
|
Malignant neoplasm of pancreas
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
B7-H3 expression was evaluated by immunohistochemistry in 68 patients with pancreatic cancer who underwent surgical tumor resection.
|
20035626 |
2009 |
|
Squamous cell carcinoma
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
B7-H3 expression in squamous cell carcinoma (SCC) was significantly higher than those in adenocarcinoma (p=0.048), while CD133 expression in large cell lung carcinoma was higher than that in SCC (p=0.023).
|
20844808 |
2010 |
|
Adenocarcinoma
|
0.030 |
AlteredExpression
|
group |
BEFREE |
B7-H3 expression in squamous cell carcinoma (SCC) was significantly higher than those in adenocarcinoma (p=0.048), while CD133 expression in large cell lung carcinoma was higher than that in SCC (p=0.023).
|
20844808 |
2010 |
|
Large cell carcinoma of lung
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
B7-H3 expression in squamous cell carcinoma (SCC) was significantly higher than those in adenocarcinoma (p=0.048), while CD133 expression in large cell lung carcinoma was higher than that in SCC (p=0.023).
|
20844808 |
2010 |