|
Hepatitis, Toxic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Characterization of chemically induced liver injuries using gene co-expression modules.
|
25226513 |
2014 |
|
Hepatitis, Drug-Induced
|
0.300 |
Biomarker
|
disease |
CTD_human |
Characterization of chemically induced liver injuries using gene co-expression modules.
|
25226513 |
2014 |
|
Drug-Induced Acute Liver Injury
|
0.300 |
Biomarker
|
disease |
CTD_human |
Characterization of chemically induced liver injuries using gene co-expression modules.
|
25226513 |
2014 |
|
Chemical and Drug Induced Liver Injury
|
0.300 |
Biomarker
|
disease |
CTD_human |
Characterization of chemically induced liver injuries using gene co-expression modules.
|
25226513 |
2014 |
|
Chemically-Induced Liver Toxicity
|
0.300 |
Biomarker
|
disease |
CTD_human |
Characterization of chemically induced liver injuries using gene co-expression modules.
|
25226513 |
2014 |
|
Myocardial Ischemia
|
0.200 |
Biomarker
|
disease |
RGD |
A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers.
|
12371906 |
2003 |
|
Malignant neoplasm of stomach
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
LC3A, LC3B and Beclin-1 Expression in Gastric Cancer.
|
30504397 |
2018 |
|
Malignant neoplasm of stomach
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Compared to the nontumor tissues, the expression of LC3B and Vimentin proteins were significantly elevated in GC tissues, but the E-cadherin expression was decreased (all <i>p</i><0.05).
|
29928144 |
2018 |
|
Malignant neoplasm of stomach
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Quantum dots (QDs)-based immunofluorescence histochemistry was used to examine the expression of fibroblastic Cav-1 and LC3B in 118 cases of GC with adequate stroma.
|
23203033 |
2012 |
|
Malignant neoplasm of stomach
|
0.060 |
Biomarker
|
disease |
BEFREE |
To investigate the clinical implication of autophagy in gastric cancer, the autophagy markers with autophagosome formation, LC3B and selective autophagy substrate p62/SQSTM1 (P62) were validated.
|
31810936 |
2019 |
|
Malignant neoplasm of stomach
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Initially, we analyzed SPHK1 expression immunohistochemically in 120 GC peritoneal tissues, and found high SPHK1 expression to be significantly associated with LC3B expression and peritoneal recurrence, leading to poor prognosis.
|
30791228 |
2019 |
|
Malignant neoplasm of stomach
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
DIRAS3 expression in GC was positively correlated with LC3B-II amount, and negatively with metastasis; DIRAS3 and p62 levels were independent prognostic factors in GC.
|
30043279 |
2018 |
|
Stomach Carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Quantum dots (QDs)-based immunofluorescence histochemistry was used to examine the expression of fibroblastic Cav-1 and LC3B in 118 cases of GC with adequate stroma.
|
23203033 |
2012 |
|
Stomach Carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
LC3A, LC3B and Beclin-1 Expression in Gastric Cancer.
|
30504397 |
2018 |
|
Stomach Carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Compared to the nontumor tissues, the expression of LC3B and Vimentin proteins were significantly elevated in GC tissues, but the E-cadherin expression was decreased (all <i>p</i><0.05).
|
29928144 |
2018 |
|
Stomach Carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Initially, we analyzed SPHK1 expression immunohistochemically in 120 GC peritoneal tissues, and found high SPHK1 expression to be significantly associated with LC3B expression and peritoneal recurrence, leading to poor prognosis.
|
30791228 |
2019 |
|
Stomach Carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
DIRAS3 expression in GC was positively correlated with LC3B-II amount, and negatively with metastasis; DIRAS3 and p62 levels were independent prognostic factors in GC.
|
30043279 |
2018 |
|
Stomach Carcinoma
|
0.060 |
Biomarker
|
disease |
BEFREE |
To investigate the clinical implication of autophagy in gastric cancer, the autophagy markers with autophagosome formation, LC3B and selective autophagy substrate p62/SQSTM1 (P62) were validated.
|
31810936 |
2019 |
|
Liver carcinoma
|
0.060 |
Biomarker
|
disease |
BEFREE |
Clinically, ANXA3 expression correlated positively with the autophagic marker LC3B in HCC and was associated with a worse overall survival in patients who went on to receive sorafenib treatment.
|
29885413 |
2018 |
|
Liver carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
In addition, an inverse association between the expression of G9A and LC3B was demonstrated in HCC tumor samples in the publically available GSE14520 dataset, which indicated that G9A may also have the potential to regulate MAP1LC3B expression in HCC tumor tissues.
|
29928350 |
2018 |
|
Liver carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Tissue microarray-based immunohistochemistry was used to examine the expression of LC3B and another autophagy key regulator (Beclin-1) in 156 operable HCC patients.
|
25256671 |
2014 |
|
Liver carcinoma
|
0.060 |
Biomarker
|
disease |
BEFREE |
Survival analysis showed that ULK1 expression were negatively correlated with PFS rather than OS in HCC patients (P=0.021), while LC3B were suggested to be negatively related with patients' PFS, However, Simultaneous high expression of ULK1 and LC3B had a poorer 5-year overall survival (OS) rate (P=0.002) and shorter 5-year progression free survival (PFS)(P=0.003), Further multivariate analysis revealed that the two combined biomarkers were independent factors to predict the prognosis of OS and PFS in all patients, while ULK1 alone or LC3B alone were only an independent predict factor for OS or PFS respectively.
|
29091866 |
2018 |
|
Liver carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we demonstrated that LC3B protein expression levels were significantly increased in the residual hepatocellular carcinoma cells after radiofrequency ablation (RFA) treatment in vivo.
|
29749472 |
2018 |
|
Liver carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
We found that restoration of miR-100 expression resulted in accumulation of LC3B-II and decrease of p62 in hepatocellular carcinoma (HCC) cells, whereas antagonism of miR-100 reduced the level of LC3B-II.
|
25026290 |
2014 |
|
Malignant neoplasm of breast
|
0.050 |
Biomarker
|
disease |
BEFREE |
Furthermore, analysis of LC3B protein in clinical breast cancer specimens and tumor xenografts revealed significant association between high Runx2 and low LC3B protein levels.
|
28345763 |
2018 |