|
Uric acid measurement (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
|
31578528 |
2019 |
|
Urolithiasis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Novel Risk Loci Identified in a Genome-Wide Association Study of Urolithiasis in a Japanese Population.
|
30975718 |
2019 |
|
Systolic Pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
|
30578418 |
2019 |
|
Malignant mesothelioma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate if aquaporin 1 (AQP1) genetic polymorphisms influence the risk of MM and the response to cisplatin based MM treatment.
|
30840592 |
2019 |
|
Glioblastoma
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
The functional Aquaporin 1 -783G/C-polymorphism is associated with survival in patients with glioblastoma multiforme.
|
24014128 |
2013 |
|
Liver Cirrhosis
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Influence of aquaporin-1 gene polymorphism on water retention in liver cirrhosis.
|
21793635 |
2011 |
|
Glioblastoma Multiforme
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
We sequenced the human AQP1-promoter to detect novel sequence variants, which might impact on Aquaporin-1-expression and tested the hypothesis, that functional single nucleotide polymorphisms are associated with different survival-times of patients suffering from GBM.
|
24014128 |
2013 |
|
Cholangiocarcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The significant expression variation of aquaporin 1 among 17 cases with cholangiocarcinoma was also found using quantitative polymerase chain reaction.
|
27143047 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Increasing evidences showed that aquaporin 1 played a role in tumor prognosis and diagnosis.
|
27143047 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Association of aquaporin‑1 with tumor migration, invasion and vasculogenic mimicry in glioblastoma multiforme.
|
29257313 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Aquaporin-1 (AQP1) is a water channel membrane protein that promotes tumour angiogenesis by allowing faster endothelial cell migration.
|
23197380 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Therefore, control of FAM188B could be a possible target to inhibit tumor growth.
|
29795372 |
2018 |
|
Tumor Cell Invasion
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
The fact that AQP-1 was highly expressed at the dural attachment and invading front of meningioma may indicate that dural invasion of the meningioma may be facilitated by AQP-1-induced water flow and neovascularization.
|
18095114 |
2006 |
|
Tumor Cell Invasion
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
Aquaporin 1 (AQP1), which functions as a water transporter, is associated with cancer cell proliferation, invasion, metastasis and angiogenesis in numerous types of solid cancer, including colorectal cancer (CRC).
|
29725400 |
2018 |
|
Tumor Cell Invasion
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
Aquaporin-1 and -5 are involved in the invasion and proliferation of soft tissue sarcomas.
|
29258764 |
2018 |
|
Tumor Cell Invasion
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
In the present study, the hypothesis that aquaporin-1 (AQP1) may participate in tumor cell proliferation, apoptosis, migration and invasion was tested using small interfering RNA (siRNA).
|
29740485 |
2018 |
|
Malignant Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Role of Aquaporin 1 Signalling in Cancer Development and Progression.
|
28146084 |
2017 |
|
Malignant Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Aquaporin 1 (AQP1), which functions as a water transporter, is associated with cancer cell proliferation, invasion, metastasis and angiogenesis in numerous types of solid cancer, including colorectal cancer (CRC).
|
29725400 |
2018 |
|
Cholestasis
|
0.040 |
Biomarker
|
disease |
BEFREE |
Hepatic gene transfer of human aquaporin-1 improves bile salt secretory failure in rats with estrogen-induced cholestasis.
|
26999313 |
2016 |
|
Cholestasis
|
0.040 |
Biomarker
|
disease |
BEFREE |
Adenoviral transfer of human aquaporin-1 gene to rat liver improves bile flow in estrogen-induced cholestasis.
|
25208977 |
2014 |
|
Hypertensive disease
|
0.040 |
Biomarker
|
group |
BEFREE |
Aqp-1 Gene Knockout Attenuates Hypoxic Pulmonary Hypertension of Mice.
|
30580569 |
2019 |
|
Hypertensive disease
|
0.040 |
Biomarker
|
group |
BEFREE |
Systemic Hypertension Effects on the Ciliary Body and Iris. An Immunofluorescence Study with Aquaporin 1, Aquaporin 4, and Na⁺, K⁺ ATPase in Hypertensive Rats.
|
30428541 |
2018 |
|
Hypertensive disease
|
0.040 |
Biomarker
|
group |
BEFREE |
Upregulated aquaporin-1 expression and function may be a response to hypertension that critically determines conduit artery vessel wall viability and long-term susceptibility to atherosclerosis.<b>NEW & NOTEWORTHY</b> The aortic endothelia of two high-renin hypertensive rat models express greater than two times the aquaporin-1 and, at low pressures, have greater than two times the endothelial hydraulic conductivity of normotensive rats.
|
28733452 |
2017 |
|
Hypertensive disease
|
0.040 |
Biomarker
|
group |
BEFREE |
Aquaporin 1 controls the functional phenotype of pulmonary smooth muscle cells in hypoxia-induced pulmonary hypertension.
|
28409279 |
2017 |
|
melanoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Aquaporin-1 inhibition reduces metastatic formation in a mouse model of melanoma.
|
29044946 |
2018 |