|
Diffuse Large B-Cell Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
<b>Aims:</b> To investigate prognostic values of GCB/non-GCB sub-categorization, Double Protein Expression Lymphoma (DPL), Triple Protein Expression Lymphoma (TPL), positivity of CD5 protein and EBER in patients with DLBCL disease.
|
31171907 |
2019 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Lack of expression of sCD5 on T-ALL blasts was correlated closely with predominant transcription of exon E1B and significant loss of exon E1A of the CD5 gene, which is associated with surface expression of CD5 on lymphocytes.
|
28752543 |
2017 |
|
Hepatitis C
|
0.010 |
Biomarker
|
disease |
BEFREE |
A lymphocyte-specific CD5 molecule was recently identified as essential for infection of T cells with native, patient-derived HCV.
|
23626783 |
2013 |
|
Thymic Squamous Cell Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The primary carcinoma showing thymus-like elements of the thyroid frequently expresses KIT and CD5 proteins; similar to thymic squamous cell carcinoma, the overexpression of KIT does not necessarily indicate a gene mutation in this tumor.
|
21835435 |
2012 |
|
Lymphoproliferative Disorders
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Despite the low incidence of microsatellite instability (MSI) in lymphoid malignant neoplasms, it has been reported that the CD5 promoter MSI was relatively frequent among B-cell chronic lymphoproliferative disorders.
|
15981803 |
2005 |
|
Mantle cell lymphoma
|
0.010 |
PosttranslationalModification
|
disease |
BEFREE |
We studied the presence of MSI in the CD5 promoter in 134 cases of B-cell chronic lymphocytic leukemia (B-CLL) and 47 of mantle cell lymphoma (MCL) by comparing the pattern of microsatellite repeats on autologous germline and tumor DNA samples.
|
15981803 |
2005 |
|
Mouth Neoplasms
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Multiplexed PCR revealed homozygous deletion of leu1 in one oral cavity tumor.
|
10502719 |
1999 |
|
Hodgkin Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
Quantitative immunophenotypic analysis of 13 cases revealed a predominance of Leu1 and Leu3 T cells in all subtypes, except in the case of HD lymphocytic-depression (HDLD).
|
8395909 |
1993 |
|
Lymphoma, Non-Hodgkin
|
0.010 |
Biomarker
|
disease |
BEFREE |
Fourteen patients with FSCCL and 1 patient with DSCCL had a phenotype of follicular center cells (FCC) (CALLA+, SIgD-, Leu-1-, Leu-8- and negative ALPase), and 11 patients with FSCCL had bcl-2 gene rearrangements.
|
1643614 |
1992 |
|
Lymphoma, Small Cleaved-Cell, Follicular
|
0.010 |
Biomarker
|
disease |
BEFREE |
Fourteen patients with FSCCL and 1 patient with DSCCL had a phenotype of follicular center cells (FCC) (CALLA+, SIgD-, Leu-1-, Leu-8- and negative ALPase), and 11 patients with FSCCL had bcl-2 gene rearrangements.
|
1643614 |
1992 |
|
Malignant transformation
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Alternatively, CD5 expression could play an additional direct role in malignant transformation as suggested by recent data on the CD5 receptor ligand.
|
1282064 |
1992 |
|
Adult Diffuse Small Cleaved Cell Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Fourteen patients with FSCCL and 1 patient with DSCCL had a phenotype of follicular center cells (FCC) (CALLA+, SIgD-, Leu-1-, Leu-8- and negative ALPase), and 11 patients with FSCCL had bcl-2 gene rearrangements.
|
1643614 |
1992 |
|
Lymphoma, Follicular, Grade 1
|
0.010 |
Biomarker
|
disease |
BEFREE |
Fourteen patients with FSCCL and 1 patient with DSCCL had a phenotype of follicular center cells (FCC) (CALLA+, SIgD-, Leu-1-, Leu-8- and negative ALPase), and 11 patients with FSCCL had bcl-2 gene rearrangements.
|
1643614 |
1992 |
|
Acute lymphocytic leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
We studied 81 cases of ALL using immunoperoxidase stain for nuclear terminal deoxynucleotidyl transferase (TdT) and immunoalkaline phosphatase stain for surface markers (using monoclonal antibody J5 for common ALL antigen [CALLA], Leu-1 for pan-T antigen, and B1 for pan-B antigen) on air-dried smears.
|
3472463 |
1987 |
|
Lymphocytosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Tumors associated with peripheral lymphocytosis more commonly expressed the Leu-1 antigen (P less than 0.01) and IgD (P less than 0.01) and less frequently were stained by BA-2 (P less than 0.05) and OKT9 (P less than 0.05).
|
3322023 |
1987 |
|
Pleural Effusion, Malignant
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Most of the cells taken from the malignant pleural effusion expressed T cell-associated antigens such as Leu-1 and OKT 8.
|
3097073 |
1986 |
|
Adult T-Cell Lymphoma/Leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
The majority of ATLL cells bear Leu-1 and Leu-3a antigen on cell surface but lack Leu-2a antigen and were unreactive with MAS 036 c. These results indicate that ATLL cells are of peripheral inducer/helper T-cell origin.
|
6600211 |
1983 |
|
Leukemia, T-Cell, Chronic
|
0.010 |
Biomarker
|
disease |
BEFREE |
A case of T-cell chronic lymphocytic leukemia (T-CLL) expressing a peculiar phenotype (E+, OKM1+, Leu 1+, OKT3- and IgG EA-).
|
6193857 |
1983 |
|
Lymphoma, T-Cell, Cutaneous
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Subtypes of cutaneous T-cell lymphoma defined by expression of leu-1 and Ia.
|
7042004 |
1982 |
|
B-Cell Lymphomas
|
0.020 |
AlteredExpression
|
group |
LHGDN |
De novo CD5+ diffuse large B-cell lymphoma: results of a detailed clinicopathological review in 120 patients.
|
18556402 |
2008 |
|
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
|
0.020 |
Biomarker
|
disease |
LHGDN |
CD5-undetected by immunohistochemistry, t(11;14)(q13;q32)-positive conjunctival mantle cell lymphoma: a case report.
|
18572329 |
2008 |
|
B-Cell Lymphomas
|
0.020 |
Biomarker
|
group |
LHGDN |
CD5-positive diffuse large B-cell lymphoma with an unusual phenotype: Cytoplasmic CD20 (+), surface CD20 (-).
|
16923582 |
2006 |
|
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
|
0.020 |
GeneticVariation
|
disease |
LHGDN |
We studied the presence of MSI in the CD5 promoter in 134 cases of B-cell chronic lymphocytic leukemia (B-CLL) and 47 of mantle cell lymphoma (MCL) by comparing the pattern of microsatellite repeats on autologous germline and tumor DNA samples.
|
15981803 |
2005 |
|
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Polymorphism in the CD5 gene promoter in B-cell chronic lymphocytic leukemia and mantle cell lymphoma.
|
15981803 |
2005 |
|
Lymphoma
|
0.020 |
Biomarker
|
group |
LHGDN |
Analysis of chromosomal imbalances in de novo CD5-positive diffuse large-B-cell lymphoma detected by comparative genomic hybridization.
|
14603444 |
2004 |