|
Status Epilepticus
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The GABA<sub>B</sub> antagonist exhibited proconvulsant effect in P15 and P18 SE as well as LiPAR rats returning the incidence of PTZ-induced seizures to values of control animals.
|
31760199 |
2020 |
|
Congenital chromosomal disease
|
0.010 |
Biomarker
|
group |
BEFREE |
However, unlike p21 deletion, absence of p27 or p18 did not increase DNA damage or chromosomal aberrations during iPSC reprogramming and at iPSC stage.
|
30894510 |
2019 |
|
Ankylosing spondylitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
These findings suggest that EEF1E1 may be an underlying genetic biomarker for the diagnosis of AS.
|
31059041 |
2019 |
|
Virus Diseases
|
0.010 |
AlteredExpression
|
group |
BEFREE |
The formation of p18 Bax resulting in cytochrome <i>c</i> release into the cytosol appeared to correlate with JEV-induced apoptotic cell death together with the activation of caspase-3/7 activity, especially during the late stage of a robust viral infection.
|
31658698 |
2019 |
|
Mental Depression
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Reliability and Validity of a Material Resources Scale and Its Association With Depression Among Young Men Who Have Sex With Men: The P18 Cohort Study.
|
27226330 |
2018 |
|
Depressive disorder
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Reliability and Validity of a Material Resources Scale and Its Association With Depression Among Young Men Who Have Sex With Men: The P18 Cohort Study.
|
27226330 |
2018 |
|
Radiation Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Upon induction of the temporal systemic deletion of AIMP3 by tamoxifen in adult mice, the animals developed an acute radiation syndrome-like phenotype, typified by scleroderma, hypotrophy of haematopoietic cells and organs, and intestinal failure.
|
30302025 |
2018 |
|
Angelman Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Ube3a ubiquinates p18, resulting in its proteasomal degradation, and Ube3a deficiency in the hippocampus of AS mice induces increased lysosomal localization of p18 and other members of the Ragulator-Rag complex, and increased mTORC1 activity. p18 knockdown in hippocampal CA1 neurons of AS mice reduces elevated mTORC1 activity and improves dendritic spine maturation, long-term potentiation (LTP), as well as learning performance.
|
30020076 |
2018 |
|
Drug usage
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Sexualised drug use among sexual minority young adults in the United States: The P18 cohort study.
|
29610012 |
2018 |
|
Depressed mood
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Reliability and Validity of a Material Resources Scale and Its Association With Depression Among Young Men Who Have Sex With Men: The P18 Cohort Study.
|
27226330 |
2018 |
|
Carcinoma of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
Overexpression of many factors predicted poor prognosis in breast (EEF1D, EEF1E1, EEF2) and lung cancer (EEF1A2, EEF1B2, EEF1G, EEF1E1).
|
29342219 |
2018 |
|
Primary malignant neoplasm of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
Overexpression of many factors predicted poor prognosis in breast (EEF1D, EEF1E1, EEF2) and lung cancer (EEF1A2, EEF1B2, EEF1G, EEF1E1).
|
29342219 |
2018 |
|
ARTERIAL TORTUOSITY SYNDROME
|
0.010 |
Biomarker
|
disease |
BEFREE |
The increase in arterial tortuosity and venous dilation were observed in the OIR eyes at P15 and P18.
|
30073364 |
2018 |
|
Multiple Chronic Conditions
|
0.010 |
Biomarker
|
disease |
BEFREE |
Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 simultaneously binds Glutamyl-Prolyl-tRNA synthetase and scaffold protein aminoacyl tRNA synthetase complex interacting multifunctional protein 3 of the multi-tRNA synthetase complex.
|
29679766 |
2018 |
|
Arthritis, Psoriatic
|
0.010 |
Biomarker
|
disease |
BEFREE |
The purpurin-18 (P18) monomer is connected to hydrophilic poly(amidoamine) dendrimer (4<sup>th</sup> generation) through a peptide (GKGSFGFTG) that can be cleaved by an autophagy-specific enzyme, i.e., ATG4B, consequently resulting in aggregation of P18 and enhanced PA signals.
|
28689116 |
2017 |
|
Ureaplasma Infections
|
0.010 |
Biomarker
|
group |
BEFREE |
A Case of Rectal Ureaplasma Infection and Implications for Testing in Young Men Who Have Sex with Men: The P18 Cohort Study.
|
28027001 |
2017 |
|
Tonic clonic movements
|
0.010 |
Biomarker
|
disease |
BEFREE |
Three ictal patterns were identified: from P9 to P12 "spike clusters" consisted of recurring large spikes without clinical correlate; "spasm-like" discharges dominated from P13 to P16 consisting of high amplitude large field potential superimposed with or followed by fast activity repeated every 2-10 s for at least 20 s, accompanied by rhythmic limb contractions; from P14 to P18 a "tonic-clonic like" pattern comprised rhythmic spikes of increasing amplitude with tonic-clonic movements.
|
26873267 |
2016 |
|
Malignant neoplasm of urinary bladder
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
TMAs derived from patients enrolled in BCON, a Phase III multicentre radiotherapy trial in bladder cancer (ISRCTN45938399) were used to evaluate the association between AIMP3 expression and survival.
|
24917520 |
2015 |
|
Bladder Neoplasm
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
TMAs derived from patients enrolled in BCON, a Phase III multicentre radiotherapy trial in bladder cancer (ISRCTN45938399) were used to evaluate the association between AIMP3 expression and survival.
|
24917520 |
2015 |
|
Carcinoma of bladder
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
TMAs derived from patients enrolled in BCON, a Phase III multicentre radiotherapy trial in bladder cancer (ISRCTN45938399) were used to evaluate the association between AIMP3 expression and survival.
|
24917520 |
2015 |
|
Carcinoma of urinary bladder, invasive
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In conclusion, AIMP3 expression is lost in a subset of bladder cancers and is significantly predictive of survival following radiotherapy in MIBC patients.
|
24917520 |
2015 |
|
Hepatitis B
|
0.010 |
Biomarker
|
disease |
BEFREE |
Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18.
|
22685290 |
2012 |
|
Lassa Fever
|
0.010 |
Biomarker
|
disease |
BEFREE |
PICV P2 strain causes a mild febrile reaction in guinea pigs, while P18 causes severe disease with clinical and pathological features reminiscent of Lassa hemorrhagic fever in humans.
|
22877842 |
2012 |
|
Liver neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18.
|
22685290 |
2012 |
|
Non-Small Cell Lung Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Although the exact biological function remains to be explored, our findings suggest possible association of polymorphisms of p18 and p21 with the prognosis of NSCLC in a Chinese population.
|
21145615 |
2011 |