|
Squamous intraepithelial lesion
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
BAG3 expression correlates with the grade of dysplasia in squamous intraepithelial lesions of the uterine cervix.
|
31444794 |
2020 |
|
precancerous lesions
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
However, nothing is known about BAG3 expression in precancerous lesions of the uterine cervix.
|
31444794 |
2020 |
|
Bipolar Disorder
|
0.010 |
Biomarker
|
disease |
BEFREE |
Patients with BD+S had higher overall impulsivity (assessed using both the UPPS-P Impulsive Behavior Scale and BIS-11) and premeditated aggression compared to patients with BD-S.
|
30658245 |
2019 |
|
Malignant neoplasm of stomach
|
0.010 |
Biomarker
|
disease |
BEFREE |
However, the role of BAG3 in progression of gastric cancer is unknown.
|
30514177 |
2019 |
|
Marijuana Abuse
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Bivariate regression analyses showed that BIS and BAS levels were associated (respectively) with the use of alcohol and cannabis.
|
31680889 |
2019 |
|
Diffuse Large B-Cell Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In the present study, the aim was to elucidate the role of the PI3K/AKT signaling pathway in the induction of BAG3, following exposure to a proteasome inhibitor in DLBCL cell lines.
|
30881494 |
2019 |
|
Depressive Symptoms
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The mediating role of BAS/BIS between hardiness and depressive symptoms was examined.
|
31263708 |
2019 |
|
Adenocarcinoma of lung (disorder)
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
<b>Conclusions:</b> Our study indicated that FAM111B might be an oncogene and potential therapeutic target in LUAD which could be involved in the regulation of tumor cells by p53 signaling pathway and play an important role in the process of cell cycle and apoptosis by influencing the expression of BAG3 and BCL2.
|
31114230 |
2019 |
|
Stomach Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
However, the role of BAG3 in progression of gastric cancer is unknown.
|
30514177 |
2019 |
|
Convulsive Seizures
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Higher BIS levels were associated with longer electric seizures duration (correlation 0.61, 95% CI [0.39-0.75], 7 studies) and longer motor seizures duration (correlation 0.72, 95% CI [0.29-0.91], 6 studies).
|
31151038 |
2019 |
|
Alexithymia
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
This study aimed at identifying specific clusters of maladaptive emotional-behavioral symptoms in adolescent victims of motorbike collisions considering their scores on alexithymia and impulsivity in addition to examining the prevalence of clinical binge eating behaviors (respectively through the Youth Self-Report (YSR), Toronto Alexithymia Scale-20 (TAS-20), Barratt Impulsiveness Scale-11 (BIS-11), and Binge Eating Scale (BES)).
|
29462976 |
2018 |
|
Behavioral Symptoms
|
0.010 |
GeneticVariation
|
group |
BEFREE |
This study aimed at identifying specific clusters of maladaptive emotional-behavioral symptoms in adolescent victims of motorbike collisions considering their scores on alexithymia and impulsivity in addition to examining the prevalence of clinical binge eating behaviors (respectively through the Youth Self-Report (YSR), Toronto Alexithymia Scale-20 (TAS-20), Barratt Impulsiveness Scale-11 (BIS-11), and Binge Eating Scale (BES)).
|
29462976 |
2018 |
|
Chondrosarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Statistical analysis showed that the expression level of BAG3 was significantly increased in the different Enneking staging of patients with chondrosarcoma and Tumor staging, and there were no statistical differences in age, gender, histological classification and tumor size.
|
29484408 |
2018 |
|
Cystic Fibrosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We also found that the BAG3 silencing-mediated correction of F508del-CFTR restores the autophagy pathway, which is defective in F508del-CFTR-expressing cells, likely because of the maladaptive stress response in CF pathophysiology.
|
29986884 |
2018 |
|
Disruptive, Impulse Control, and Conduct Disorders
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Among patients with ICD, impulsivity was correlated with ICD severity (BIS-11 <i>r</i> = 0.33, <i>p</i> = 0.001, adjusted <i>p</i> = 0.002, CE <i>r</i> = 0.53, <i>p</i> = 0.006).
|
30323775 |
2018 |
|
Multiple Sclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
In the subgroup of individuals with a BDI-SF< 8, the BIS-11 cognitive subscale scores were significantly higher in patients with MS than in subjects without MS (p = 0.041).
|
29705607 |
2018 |
|
Self-Injurious Behavior
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Participants were evaluated at the beginning and at the end of the follow-up period using the rating scales that showed a significant difference between the groups after the 12-week trial with fatty acids supplementation: the Borderline Personality Disorder Severity Index (BPDSI) (items 'impulsivity' and 'outbursts of anger'), Barratt Impulsiveness Scale-Version 11 (BIS-11), and Self Harm Inventory (SHI).
|
29302857 |
2018 |
|
Benign Neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
BAG3 was significantly increased in chondrosarcoma cells and tissues compared with the normal cartilage cells, tissue and cartilage benign tumors.
|
29484408 |
2018 |
|
Abnormal behavior
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The total scores of BIS-11 of the AID group reported the highest score compared with other psychiatric disorders.
|
29132075 |
2018 |
|
Anaplastic thyroid carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Identification of BAG3 target proteins in anaplastic thyroid cancer cells by proteomic analysis.
|
29487711 |
2018 |
|
Drug usage
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Glutamate concentration was positively correlated with the duration of drug use (<i>r</i> = 0.401, <i>p</i> = 0.035) and the total dose of regular addiction (duration of addiction × regular addiction dose; <i>r</i> = 0.207, <i>p</i> = .040), but not with BIS-11 scores.
|
30233420 |
2018 |
|
Infectious pustular vulvovaginitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
BAG3 is a multifunctional protein that can bind to heat shock proteins (Hsp) 70 through its BAG domain and to other partners through its WW domain, proline-rich (PXXP) repeat and IPV (Ile-Pro-Val) motifs.
|
28864347 |
2018 |
|
Eichsfeld type congenital muscular dystrophy
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Rigid spine syndrome associated with sensory-motor axonal neuropathy resembling Charcot-Marie-Tooth disease is characteristic of Bcl-2-associated athanogene-3 gene mutations even without cardiac involvement.
|
28224639 |
2018 |
|
cardiac event
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
The presence of BAG3 variants was associated with a nearly 2-fold (hazard ratio, 1.97 [95% CI, 1.19-3.24]; P = .01) increase in cardiac events in carriers compared with noncarriers.
|
30140897 |
2018 |
|
Impulsive aggression
|
0.010 |
Biomarker
|
disease |
BEFREE |
The IA subscale is correlated with BIS-11 attentional, motor, and non-planning impulsiveness dimensions (<i>p</i> < 0.05).
|
29472874 |
2018 |