CHEK2, checkpoint kinase 2, 11200

N. diseases: 5; N. variants: 16
Disease: Malignant neoplasm of prostate ×
Source: UNIPROT ×
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs587780194
rs587780194 		1.000 0.080 22 28699866 missense variant T/A;C snv 1.6E-05
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 1.000 5 2008 2015
dbSNP: rs750984976
rs750984976 		1.000 0.080 22 28699879 missense variant T/C;G snv 4.0E-06
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 1.000 5 2008 2015
dbSNP: rs77130927
rs77130927 		0.882 0.120 22 28725031 missense variant G/A snv 1.0E-03 5.5E-04
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 1.000 5 2008 2015
dbSNP: rs121908701
rs121908701 		1.000 0.080 22 28725027 missense variant C/T snv 1.4E-04 6.3E-05
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 0
dbSNP: rs121908702
rs121908702 		0.882 0.120 22 28711986 stop gained C/A;G;T snv 8.0E-06; 4.0E-06; 7.6E-05
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 0
dbSNP: rs137853009
rs137853009 		0.925 0.080 22 28725030 missense variant C/A;T snv 4.0E-06; 6.0E-05
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 0
dbSNP: rs137853010
rs137853010 		0.882 0.120 22 28725028 missense variant G/A;C snv 1.1E-04
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 0
dbSNP: rs141568342
rs141568342 		1.000 0.080 22 28734532 missense variant C/T snv 1.6E-04 1.5E-04
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 0
dbSNP: rs143611747
rs143611747 		1.000 0.080 22 28699893 missense variant C/A;G;T snv 4.0E-06; 8.0E-06; 4.0E-06; 4.8E-05
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 0
dbSNP: rs587780189
rs587780189 		1.000 0.080 22 28711950 missense variant T/A snv 8.0E-06 8.4E-05
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 0
dbSNP: rs587781667
rs587781667 		1.000 0.080 22 28725253 missense variant C/G;T snv 8.0E-06; 1.6E-05
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 0
dbSNP: rs72552322
rs72552322 		0.925 0.120 22 28725070 missense variant C/T snv 2.4E-05 7.0E-06
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.700 0