KLK3, kallikrein related peptidase 3, 354

N. diseases: 358; N. variants: 19
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs62113212
rs62113212 		0.925 0.080 19 50857584 non coding transcript exon variant C/G;T snv
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.710 0.500 2 2011 2015
dbSNP: rs1192131078
rs1192131078 		0.925 0.080 19 50858075 missense variant G/A snv 4.0E-06
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1192131078
rs1192131078 		0.925 0.080 19 50858075 missense variant G/A snv 4.0E-06
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1325243071
rs1325243071 		1.000 0.120 19 50858291 missense variant T/C snv
CUI: C0878773
Disease: Overactive Bladder
Overactive Bladder 		Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1450063773
rs1450063773 		0.925 0.080 19 50858491 missense variant C/A;T snv 8.0E-06; 4.0E-06
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2003 2003
dbSNP: rs1450063773
rs1450063773 		0.925 0.080 19 50858491 missense variant C/A;T snv 8.0E-06; 4.0E-06
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2006 2006
dbSNP: rs1450063773
rs1450063773 		0.925 0.080 19 50858491 missense variant C/A;T snv 8.0E-06; 4.0E-06
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2003 2003
dbSNP: rs538660698
rs538660698 		0.882 0.200 19 50860077 missense variant G/A;T snv 8.0E-06
CUI: C0268398
Disease: Familial lichen amyloidosis
Familial lichen amyloidosis 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases 0.010 1.000 1 2011 2011
dbSNP: rs538660698
rs538660698 		0.882 0.200 19 50860077 missense variant G/A;T snv 8.0E-06
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2011 2011
dbSNP: rs538660698
rs538660698 		0.882 0.200 19 50860077 missense variant G/A;T snv 8.0E-06
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2011 2011
dbSNP: rs62113212
rs62113212 		0.925 0.080 19 50857584 non coding transcript exon variant C/G;T snv
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 < 0.001 1 2011 2011
dbSNP: rs765521022
rs765521022 		0.851 0.080 19 50858171 missense variant T/C snv
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2005 2005
dbSNP: rs765521022
rs765521022 		0.851 0.080 19 50858171 missense variant T/C snv
CUI: C1282496
Disease: Metastasis from malignant tumor of prostate
Metastasis from malignant tumor of prostate 		0.010 1.000 1 2005 2005
dbSNP: rs765521022
rs765521022 		0.851 0.080 19 50858171 missense variant T/C snv
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2005 2005
dbSNP: rs765521022
rs765521022 		0.851 0.080 19 50858171 missense variant T/C snv
CUI: C0936223
Disease: Metastatic Prostate Carcinoma
Metastatic Prostate Carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2005 2005
dbSNP: rs776973438
rs776973438 		1.000 19 50860060 missense variant C/T snv 4.0E-06
CUI: C1739135
Disease: Progression of prostate cancer
Progression of prostate cancer 		0.010 1.000 1 2011 2011
dbSNP: rs781327047
rs781327047 		0.925 0.080 19 50856344 missense variant G/A;C snv 4.0E-06; 4.0E-06
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2016 2016
dbSNP: rs781327047
rs781327047 		0.925 0.080 19 50856344 missense variant G/A;C snv 4.0E-06; 4.0E-06
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2016 2016
dbSNP: rs369223448
rs369223448 		0.925 0.080 19 50856347 missense variant G/A snv 3.6E-05 1.4E-05
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2016 2016
dbSNP: rs369223448
rs369223448 		0.925 0.080 19 50856347 missense variant G/A snv 3.6E-05 1.4E-05
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2016 2016
dbSNP: rs746367915
rs746367915 		0.925 0.080 19 50860089 missense variant C/T snv 8.0E-06 2.8E-05
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.020 1.000 2 2005 2010
dbSNP: rs746367915
rs746367915 		0.925 0.080 19 50860089 missense variant C/T snv 8.0E-06 2.8E-05
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.020 1.000 2 2005 2010
dbSNP: rs149709822
rs149709822 		0.882 0.080 19 50856335 missense variant G/A snv 4.0E-05 2.3E-04
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.040 0.750 4 2000 2008
dbSNP: rs149709822
rs149709822 		0.882 0.080 19 50856335 missense variant G/A snv 4.0E-05 2.3E-04
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.040 0.500 4 2001 2008
dbSNP: rs149709822
rs149709822 		0.882 0.080 19 50856335 missense variant G/A snv 4.0E-05 2.3E-04
CUI: C1704272
Disease: Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia 		Male Urogenital Diseases 0.020 0.500 2 2002 2005