NRXN1, neurexin 1, 9378

N. diseases: 139; N. variants: 41
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1045881
rs1045881 		1.000 0.040 2 49921834 3 prime UTR variant C/T snv 0.15
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 < 0.001 1 2011 2011
dbSNP: rs1558507406
rs1558507406 		1.000 2 49922173 frameshift variant -/CCGT delins
CUI: C3808494
Disease: CHROMOSOME 2p16.3 DELETION SYNDROME
CHROMOSOME 2p16.3 DELETION SYNDROME 		0.700 0
dbSNP: rs11681792
rs11681792 		1.000 0.080 2 49957256 intron variant C/T snv 0.12
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		Chemically-Induced Disorders; Mental Disorders 0.700 1.000 1 2013 2013
dbSNP: rs11681792
rs11681792 		1.000 0.080 2 49957256 intron variant C/T snv 0.12
CUI: C0236664
Disease: Alcohol-Related Disorders
Alcohol-Related Disorders 		Chemically-Induced Disorders; Mental Disorders 0.700 1.000 1 2013 2013
dbSNP: rs11681792
rs11681792 		1.000 0.080 2 49957256 intron variant C/T snv 0.12
CUI: C0236970
Disease: Alcohol-Induced Disorders
Alcohol-Induced Disorders 		Chemically-Induced Disorders 0.700 1.000 1 2013 2013
dbSNP: rs11681792
rs11681792 		1.000 0.080 2 49957256 intron variant C/T snv 0.12
CUI: C0001948
Disease: Alcohol consumption
Alcohol consumption 		Behavior and Behavior Mechanisms 0.700 1.000 1 2013 2013
dbSNP: rs9636391
rs9636391 		2 49973972 missense variant A/G snv 0.85 0.82
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 1.000 2 2019 2019
dbSNP: rs930295
rs930295 		2 50006214 intron variant A/C snv 0.89
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 1.000 1 2019 2019
dbSNP: rs1421589
rs1421589 		1.000 0.080 2 50063015 intron variant A/G;T snv
CUI: C0019569
Disease: Hirschsprung Disease
Hirschsprung Disease 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases 0.010 1.000 1 2018 2018
dbSNP: rs930752
rs930752 		2 50109355 intron variant C/A snv 0.23
CUI: C0852733
Disease: Completed Suicide
Completed Suicide 		0.010 1.000 1 2012 2012
dbSNP: rs6545155
rs6545155 		2 50202723 intron variant T/C snv 0.28
CUI: C0871470
Disease: Systolic Pressure
Systolic Pressure 		0.700 1.000 1 2018 2018
dbSNP: rs199546979
rs199546979 		1.000 0.080 2 50236836 stop gained G/A snv
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.700 0
dbSNP: rs1356888
rs1356888 		2 50288880 intron variant T/A;C snv
CUI: C0023980
Disease: Longevity
Longevity 		0.800 1.000 1 2010 2010
dbSNP: rs2139629
rs2139629 		2 50400459 intron variant A/G snv 0.26
CUI: C0871470
Disease: Systolic Pressure
Systolic Pressure 		0.700 1.000 1 2019 2019
dbSNP: rs10187911
rs10187911 		0.882 0.080 2 50420809 intron variant C/A;G;T snv
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2013 2013
dbSNP: rs10187911
rs10187911 		0.882 0.080 2 50420809 intron variant C/A;G;T snv
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2013 2013
dbSNP: rs10187911
rs10187911 		0.882 0.080 2 50420809 intron variant C/A;G;T snv
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2013 2013
dbSNP: rs10865246
rs10865246 		1.000 0.080 2 50443116 intron variant C/A;T snv
CUI: C0028043
Disease: Nicotine Dependence
Nicotine Dependence 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2016 2016
dbSNP: rs112638127
rs112638127 		1.000 0.040 2 50472460 missense variant T/C snv 4.0E-05 4.2E-05
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 < 0.001 1 2011 2011
dbSNP: rs267606922
rs267606922 		1.000 2 50496039 stop gained G/C snv 4.1E-06
CUI: C3280479
Disease: PITT-HOPKINS-LIKE SYNDROME 2
PITT-HOPKINS-LIKE SYNDROME 2 		0.700 0
dbSNP: rs6754640
rs6754640 		2 50504180 intron variant G/A;T snv
CUI: C0039474
Disease: Temperament
Temperament 		Behavior and Behavior Mechanisms 0.700 1.000 1 2012 2012
dbSNP: rs1014667
rs1014667 		2 50521617 intron variant G/A;C snv
CUI: C1519383
Disease: Smoking Behaviors
Smoking Behaviors 		Behavior and Behavior Mechanisms 0.700 1.000 1 2015 2015
dbSNP: rs1014667
rs1014667 		2 50521617 intron variant G/A;C snv
CUI: C0037369
Disease: Smoking
Smoking 		Behavior and Behavior Mechanisms 0.700 1.000 1 2015 2015
dbSNP: rs758352860
rs758352860 		1.000 0.040 2 50531232 missense variant T/C snv 8.1E-06
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders 		Mental Disorders 0.010 1.000 1 2019 2019
dbSNP: rs768913131
rs768913131 		0.925 0.040 2 50552821 missense variant G/A snv
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders 		Mental Disorders 0.010 1.000 1 2004 2004