DisGeNET - a database of gene-disease associations

FAM13A, family with sequence similarity 13 member A, 10144

N. diseases: 64; N. variants: 66

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs4416442

Entrez Id:	10144;105377327
Gene Symbol:	FAM13A;LOC105377327

FAM13A;LOC105377327

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.700

GeneticVariation

GWASCAT

Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease.

25241909

2014

dbSNP:

rs4416442

Entrez Id:	10144;105377327
Gene Symbol:	FAM13A;LOC105377327

FAM13A;LOC105377327

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.700

GeneticVariation

GWASCAT

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.

24621683

2014

dbSNP:

rs6837671

Entrez Id:	10144;105377327
Gene Symbol:	FAM13A;LOC105377327

FAM13A;LOC105377327

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.700

GeneticVariation

GWASCAT

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

28166215

2017

dbSNP:

rs7671261

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.700

GeneticVariation

GWASCAT

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.

30804561

2019

dbSNP:

rs7674369

Entrez Id:	10144;105377327
Gene Symbol:	FAM13A;LOC105377327

FAM13A;LOC105377327

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.700

GeneticVariation

GWASCAT

IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease.

25101718

2015

dbSNP:

rs17014601

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.010

GeneticVariation

BEFREE

The results suggest that the new variant rs17014601 in the <i>FAM13A</i> gene was significantly associated with COPD risk in a Chinese rural population.

29872291

2018

dbSNP:

rs2013701

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.010

GeneticVariation

BEFREE

MPRAs identified multiple functional variants in this region, including rs2013701, a putative COPD-causing variant with allele-specific regulatory activity.

30079747

2019

dbSNP:

rs6830970

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.010

GeneticVariation

BEFREE

Five SNPs (rs7671167, rs2869966, rs2869967, rs2045517, and rs6830970) were associated with FEV1/FVC ratio in the entire cohort and rs6830970 was associated with FEV1/FVC ratio in COPD cases (P range 0.003-0.034).

23891779

2013

dbSNP:

rs3822072

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0578022
Disease:

Finding of body mass index

0.700

GeneticVariation

GWASDB

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.

22885924

2012

dbSNP:

rs2869967

Entrez Id:	10144;105377327
Gene Symbol:	FAM13A;LOC105377327

FAM13A;LOC105377327

CUI:	C0016529
Disease:

Forced expiratory volume function

0.800

GeneticVariation

GWASDB

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.

23284291

2012

dbSNP:

rs2869967

Entrez Id:	10144;105377327
Gene Symbol:	FAM13A;LOC105377327

FAM13A;LOC105377327

CUI:	C0016529
Disease:

Forced expiratory volume function

0.800

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs10015415

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs10019681

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs10021465

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs10028589

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs12648534

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs147089648

Entrez Id:	10144;105377327
Gene Symbol:	FAM13A;LOC105377327

FAM13A;LOC105377327

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs1708667

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs1795720

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs1795739

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs1812329

Entrez Id:	10144;105377327
Gene Symbol:	FAM13A;LOC105377327

FAM13A;LOC105377327

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs1964516

Entrez Id:	10144;105377327
Gene Symbol:	FAM13A;LOC105377327

FAM13A;LOC105377327

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs2013701

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs2045517

Entrez Id:	10144;105377327
Gene Symbol:	FAM13A;LOC105377327

FAM13A;LOC105377327

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs2178586

Entrez Id:	10144
Gene Symbol:	FAM13A

FAM13A

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015