RCL1, RNA terminal phosphate cyclase like 1, 10171

N. diseases: 19; N. variants: 43
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1053872
rs1053872
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASDB Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs1053872
rs1053872
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs1053872
rs1053872
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE Additionally, combined analysis of the two high-risk SNPs revealed that subjects carrying the variant genotypes of rs462480 and rs1053872 had increased risk of breast cancer in a dose-response manner (P(trend) = 0.002). 24475105 2014
dbSNP: rs1053872
rs1053872
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE Additionally, combined analysis of the two high-risk SNPs revealed that subjects carrying the variant genotypes of rs462480 and rs1053872 had increased risk of breast cancer in a dose-response manner (P(trend) = 0.002). 24475105 2014
dbSNP: rs10739069
rs10739069
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0427460
Disease:
Red cell distribution width determination 		A 0.700 GeneticVariation GWASCAT Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. 28957414 2017
dbSNP: rs10739069
rs10739069
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C1304746
Disease:
RDW - Red blood cell distribution width result 		A 0.700 GeneticVariation GWASCAT Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. 28957414 2017
dbSNP: rs10758656
rs10758656
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.800 GeneticVariation GWASDB Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10758656
rs10758656
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.800 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs10758656
rs10758656
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0206161
Disease:
Reticulocyte count (procedure) 		G 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs10758656
rs10758656
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs10758656
rs10758656
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0427460
Disease:
Red cell distribution width determination 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs10758656
rs10758656
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs10758656
rs10758656
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		A 0.700 GeneticVariation GWASCAT Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. 28017375 2017
dbSNP: rs10758656
rs10758656
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C1304746
Disease:
RDW - Red blood cell distribution width result 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs10758656
rs10758656
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs10758657
rs10758657
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean 		0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs10758657
rs10758657
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASDB Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		0.800 GeneticVariation GWASCAT Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. 28017375 2017
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		A 0.800 GeneticVariation GWASDB Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		A 0.800 GeneticVariation GWASCAT Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. 28017375 2017
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		A 0.800 GeneticVariation GWASDB Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		A 0.800 GeneticVariation GWASCAT Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		A 0.800 GeneticVariation GWASCAT Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. 19862010 2009
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. 28017375 2017
dbSNP: rs10758658
rs10758658
Entrez Id: 10171
Gene Symbol: RCL1
RCL1
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018