HOXB13, homeobox B13, 10481

N. diseases: 90; N. variants: 3
Disease: Neoplastic Syndromes, Hereditary ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR HOXB13 mutations and binding partners in prostate development and cancer: Function, clinical significance, and future directions. 28798948 2017
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes. 27902461 2017
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Recurrent HOXB13 mutations in the Dutch population do not associate with increased breast cancer risk. 27424772 2016
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer. 27153395 2016
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Oncogenic mechanisms of HOXB13 missense mutations in prostate carcinogenesis. 28050579 2016
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Prevalence of the HOXB13 G84E mutation in Danish men undergoing radical prostatectomy and its correlations with prostate cancer risk and aggressiveness. 26779768 2016
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR The HOXB13 G84E Mutation Is Associated with an Increased Risk for Prostate Cancer and Other Malignancies. 26108461 2015
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Imputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohort. 25629170 2015
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Germline HOXB13 p.Gly84Glu mutation and cancer susceptibility: a pooled analysis of 25 epidemiological studies with 145,257 participates. 26517352 2015
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Prevalence of the HOXB13 G84E mutation among unaffected men with a family history of prostate cancer. 24310616 2014
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR G84E mutation in HOXB13 is firmly associated with prostate cancer risk: a meta-analysis. 24026887 2014
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Dysregulation of the homeobox transcription factor gene HOXB13: role in prostate cancer. 25206306 2014
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR A population-based assessment of germline HOXB13 G84E mutation and prostate cancer risk. 22841674 2014
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Germline homeobox B13 (HOXB13) G84E mutation and prostate cancer risk in European descendants: a meta-analysis of 24,213 cases and 73, 631 controls. 23518396 2013
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trial. 23393222 2013
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG). 23064873 2013
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Population-based estimate of prostate cancer risk for carriers of the HOXB13 missense mutation G84E. 23457453 2013
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR HOXB13 G84E mutation in Finland: population-based analysis of prostate, breast, and colorectal cancer risk. 23292082 2013
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer. 23541221 2013
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Association of a HOXB13 variant with breast cancer. 22853031 2012
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Confirmation of the HOXB13 G84E germline mutation in familial prostate cancer. 22714738 2012
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Germline mutations in HOXB13 and prostate-cancer risk. 22236224 2012
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Association between germline HOXB13 G84E mutation and risk of prostate cancer. 22781434 2012
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Posterior Hox gene expression and differential androgen regulation in the developing and adult rat prostate lobes. 17138648 2007
dbSNP: rs138213197
rs138213197
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0027672
Disease:
Neoplastic Syndromes, Hereditary 		T 0.700 GeneticVariation CLINVAR Hoxb13 up-regulates transglutaminase activity and drives terminal differentiation in an epidermal organotypic model. 15964834 2005