TMC1, transmembrane channel like 1, 117531

N. diseases: 16; N. variants: 23
Disease: social stress ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1630623
rs1630623
Entrez Id: 117531
Gene Symbol: TMC1
TMC1
CUI: C0871388
Disease:
social stress 		0.010 GeneticVariation BEFREE Three of the GWS loci identified (rs200889048, rs12490016 and rs1630623) were not previously reported by GWAS of BMI in the general population, and two of them raise interesting hypotheses: rs12490016-a regulatory variant located within LINC00880, where there are other GWAS-identified variants associated with birth size, adiposity in newborns and bulimia symptoms, which also interact with social stress in relation to birth size; rs1630623-a regulatory variant related to ALDH1A1, a gene involved in alcohol metabolism and adipocyte plasticity. 26458734 2017