Disease: Crohn Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1042058
rs1042058
Entrez Id: 1326
Gene Symbol: MAP3K8
MAP3K8
CUI: C0010346
Disease:
Crohn Disease 		0.710 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
dbSNP: rs1042058
rs1042058
Entrez Id: 1326
Gene Symbol: MAP3K8
MAP3K8
CUI: C0010346
Disease:
Crohn Disease 		0.710 GeneticVariation BEFREE Finally, rs1042058 GG risk carrier MDMs from healthy individuals and patients with Crohn's disease had increased TPL2 expression and NOD2-initiated TPL2 phosphorylation, ERK, JNK and NFκB activation, and early autocrine IL-1β and IL-18 secretion. 26215868 2016
dbSNP: rs1042058
rs1042058
Entrez Id: 1326
Gene Symbol: MAP3K8
MAP3K8
CUI: C0010346
Disease:
Crohn Disease 		G 0.710 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015