ADRA1A, adrenoceptor alpha 1A, 148

N. diseases: 294; N. variants: 30
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs773249771
rs773249771
Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
CUI: C4086165
Disease:
Childhood Neuroblastoma 		0.010 GeneticVariation BEFREE Next, the neuroblastoma cells were transfected with the wild type GRK2 or its dominant negative mutant GRK2-K220R and the inhibition on cAMP level was determined in naïve and agonist-pretreated cells. 18395423 2008
dbSNP: rs773249771
rs773249771
Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
CUI: C0700095
Disease:
Central neuroblastoma 		0.010 GeneticVariation BEFREE Next, the neuroblastoma cells were transfected with the wild type GRK2 or its dominant negative mutant GRK2-K220R and the inhibition on cAMP level was determined in naïve and agonist-pretreated cells. 18395423 2008
dbSNP: rs965041152
rs965041152
Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE Using whole exome sequencing, we identified a rare heterozygous variant (c.545G>T; p.Cys182Phe) in Trace amine associated receptor 1 gene (TAAR1 6q23.2) in three affected members in a small SZ family. 28242106 2017