ACE, angiotensin I converting enzyme, 1636

N. diseases: 1082; N. variants: 82
Disease: Diabetic Nephropathy ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799752
rs1799752
Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease:
Diabetic Nephropathy 		0.020 GeneticVariation BEFREE Minor allele frequency of rs1800764 was higher in DN patients than DWN patients or healthy controls, and minor allele frequency of rs1799752 was higher in DN than DWN patients. 19787680 2009
dbSNP: rs1799752
rs1799752
Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease:
Diabetic Nephropathy 		0.020 GeneticVariation BEFREE In the case-control analysis, the rs1800764-C, rs4311-T, Insertion/deletion (I/D or rs1799752)-D, rs4366-G, and rs12449782-G alleles were associated with an increased risk for DN, homogeneously across populations, with allelic odds ratios of 1.11 (95% confidence interval 1.00 to 1.22), 1.18 (1.04 to 1.33), 1.13 (1.02 to 1.23), 1.10 (0.99 to 1.20), and 1.12 (1.01 to 1.23), respectively. 17376814 2007