DNM1, dynamin 1, 1759

N. diseases: 114; N. variants: 19
Disease: Nicotine Dependence ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3003609
rs3003609
Entrez Id: 1759
Gene Symbol: DNM1
DNM1
CUI: C0028043
Disease:
Nicotine Dependence 		0.010 GeneticVariation BEFREE Finally, by using in vitro gene expression assays, we demonstrated that the T allele of rs3003609 in the exon 9 of DNM1 significantly decreases the expression of DNM1, by 27.1% at the mRNA and 22.0% at the protein level, suggesting that rs3003609 represents a functional polymorphism affecting DNM1 expression and may partly contributed to the observed association of the gene with ND in our samples. 18987626 2009