AGTR1, angiotensin II receptor type 1, 185

N. diseases: 440; N. variants: 33
Disease: Hypertensive disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2638360
rs2638360
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE Moreover, among the eight SNPs not individually associated with hypertension (rs12631819, rs2920502, rs1175543, and rs2972164 in the PPARG gene, and rs2638360, rs1492100, rs5182, and rs275646 in the AGTR1 gene), the two-locus model involving rs12631819 and rs5182 demonstrated increased susceptibility to hypertension, and the five-locus model involving rs12631819, rs2920502, rs2972164, rs5182, and rs2638360 demonstrated a significantly decreased risk of hypertension. 29266977 2018