AGTR1, angiotensin II receptor type 1, 185

N. diseases: 440; N. variants: 33
Disease: Hypertensive disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5182
rs5182
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease:
Hypertensive disease 		0.030 GeneticVariation BEFREE Moreover, among the eight SNPs not individually associated with hypertension (rs12631819, rs2920502, rs1175543, and rs2972164 in the PPARG gene, and rs2638360, rs1492100, rs5182, and rs275646 in the AGTR1 gene), the two-locus model involving rs12631819 and rs5182 demonstrated increased susceptibility to hypertension, and the five-locus model involving rs12631819, rs2920502, rs2972164, rs5182, and rs2638360 demonstrated a significantly decreased risk of hypertension. 29266977 2018
dbSNP: rs5182
rs5182
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease:
Hypertensive disease 		0.030 GeneticVariation BEFREE Although the AGTR1 SNP did not show any association with WMLs, the interaction of the AGT rs699 and AGTR1 rs5182 SNPs with WMLs was significant before (P = 0.03) and after adjustment for hypertension (P = 0.045). 24622918 2014
dbSNP: rs5182
rs5182
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease:
Hypertensive disease 		0.030 GeneticVariation BEFREE The results suggest that the rs5182 gene polymorphism could be involved in the risk of developing hypertension in Mexican individuals. 21846682 2012