FLT3, fms related receptor tyrosine kinase 3, 2322

N. diseases: 270; N. variants: 54
Disease: Leukemia, Myelocytic, Acute ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519726
rs1057519726
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 CausalMutation CLINVAR Mutational landscape of AML with normal cytogenetics: biological and clinical implications. 23261068 2013
dbSNP: rs1057519726
rs1057519726
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 CausalMutation CLINVAR The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia. 23783394 2013
dbSNP: rs1057519726
rs1057519726
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 CausalMutation CLINVAR Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia. 23321257 2013
dbSNP: rs1057519726
rs1057519726
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 CausalMutation CLINVAR The role of kinase inhibitors in the treatment of patients with acute myeloid leukemia. 23714533 2013
dbSNP: rs1057519726
rs1057519726
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 CausalMutation CLINVAR Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation. 22368270 2012
dbSNP: rs1057519726
rs1057519726
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 CausalMutation CLINVAR Continuing aspirin in the perioperative patient. 22504186 2012
dbSNP: rs1057519726
rs1057519726
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation CLINVAR Novel observation of three FLT3 codons mutated in tandem in an elderly acute myeloid leukaemia patient. 16371029 2006
dbSNP: rs1057519726
rs1057519726
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		C 0.700 GeneticVariation CLINVAR Prospective study of 174 de novo acute myelogenous leukemias according to the WHO classification: subtypes, cytogenetic features and FLT3 mutations. 16573742 2006
dbSNP: rs1057519726
rs1057519726
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 CausalMutation CLINVAR Prognostic significance of FLT3 mutations in pediatric non-promyelocytic acute myeloid leukemia. 15863200 2005