DisGeNET - a database of gene-disease associations

CLEC16A, C-type lectin domain containing 16A, 23274

N. diseases: 67; N. variants: 62

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs17673553

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0011854
Disease:

Diabetes Mellitus, Insulin-Dependent

0.710

GeneticVariation

BEFREE

Three common non-coding variants of the gene (rs2903692, rs725613 and rs17673553) in strong linkage disequilibrium reached genome-wide significance for association with T1D.

17632545

2007

dbSNP:

rs12924112

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0341106
Disease:

Eosinophilic esophagitis

0.700

GeneticVariation

GWASCAT

Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis.

29904099

2019

dbSNP:

rs12935657

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0264408
Disease:

Childhood asthma

0.700

GeneticVariation

GWASCAT

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

30929738

2019

dbSNP:

rs12935657

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0004096
Disease:

Asthma

0.700

GeneticVariation

GWASCAT

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

30929738

2019

dbSNP:

rs248831

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0023508
Disease:

White Blood Cell Count procedure

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs35032408

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0264408
Disease:

Childhood asthma

0.700

GeneticVariation

GWASCAT

Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

31036433

2019

dbSNP:

rs35032408

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0741260
Disease:

Adult onset asthma

0.700

GeneticVariation

GWASCAT

Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

31036433

2019

dbSNP:

rs35441874

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0741260
Disease:

Adult onset asthma

0.700

GeneticVariation

GWASCAT

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

30929738

2019

dbSNP:

rs35441874

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0004096
Disease:

Asthma

0.700

GeneticVariation

GWASCAT

Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

31619474

2019

dbSNP:

rs35441874

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0004096
Disease:

Asthma

0.700

GeneticVariation

GWASCAT

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

30929738

2019

dbSNP:

rs35441874

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0013595
Disease:

Eczema

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs36045143

Entrez Id:	23274;105371081
Gene Symbol:	CLEC16A;LOC105371081

CLEC16A;LOC105371081

CUI:	C0035242
Disease:

Respiratory Tract Diseases

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs62026377

Entrez Id:	23274;105371081
Gene Symbol:	CLEC16A;LOC105371081

CLEC16A;LOC105371081

CUI:	C0200638
Disease:

Eosinophil count procedure

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs7203459

Entrez Id:	23274;105371081
Gene Symbol:	CLEC16A;LOC105371081

CLEC16A;LOC105371081

CUI:	C0004096
Disease:

Asthma

0.700

GeneticVariation

GWASCAT

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

30552067

2019

dbSNP:

rs8061043

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0200638
Disease:

Eosinophil count procedure

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs876476

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0205682
Disease:

Waist-Hip Ratio

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs11644510

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C2607914
Disease:

Allergic rhinitis (disorder)

0.700

GeneticVariation

GWASCAT

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

30013184

2018

dbSNP:

rs11645657

Entrez Id:	23274;105371081
Gene Symbol:	CLEC16A;LOC105371081

CLEC16A;LOC105371081

CUI:	C0004096
Disease:

Asthma

0.700

GeneticVariation

GWASCAT

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

29785011

2018

dbSNP:

rs11645657

Entrez Id:	23274;105371081
Gene Symbol:	CLEC16A;LOC105371081

CLEC16A;LOC105371081

CUI:	C1527304
Disease:

Allergic Reaction

0.700

GeneticVariation

GWASCAT

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

29785011

2018

dbSNP:

rs17806299

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0004096
Disease:

Asthma

0.700

GeneticVariation

GWASCAT

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

29273806

2018

dbSNP:

rs17806299

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0004096
Disease:

Asthma

0.700

GeneticVariation

GWASCAT

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

29273806

2018

dbSNP:

rs36045143

Entrez Id:	23274;105371081
Gene Symbol:	CLEC16A;LOC105371081

CLEC16A;LOC105371081

CUI:	C1527304
Disease:

Allergic Reaction

0.700

GeneticVariation

GWASCAT

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

29785011

2018

dbSNP:

rs36045143

Entrez Id:	23274;105371081
Gene Symbol:	CLEC16A;LOC105371081

CLEC16A;LOC105371081

CUI:	C0004096
Disease:

Asthma

0.700

GeneticVariation

GWASCAT

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

29785011

2018

dbSNP:

rs11644510

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C1527304
Disease:

Allergic Reaction

0.700

GeneticVariation

GWASCAT

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.

29083406

2017

dbSNP:

rs2041670

Entrez Id:	23274
Gene Symbol:	CLEC16A

CLEC16A

CUI:	C0024141
Disease:

Lupus Erythematosus, Systemic

0.700

GeneticVariation

GWASCAT

Transancestral mapping and genetic load in systemic lupus erythematosus.

28714469

2017