ALK, ALK receptor tyrosine kinase, 238

N. diseases: 519; N. variants: 41
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs863225285
rs863225285
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		G 0.700 CausalMutation CLINVAR
dbSNP: rs864309584
rs864309584
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.700 GeneticVariation UNIPROT
dbSNP: rs281864719
rs281864719
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		G 0.700 GeneticVariation CLINVAR Valproate-induced hepatoxicity: protective effect of L-carnitine supplementation. 2124297 1990
dbSNP: rs113994091
rs113994091
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.800 GeneticVariation UNIPROT Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359 2008
dbSNP: rs113994092
rs113994092
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.800 GeneticVariation UNIPROT Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359 2008
dbSNP: rs281864719
rs281864719
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.800 GeneticVariation UNIPROT Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359 2008
dbSNP: rs281864720
rs281864720
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.800 GeneticVariation UNIPROT Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359 2008
dbSNP: rs1057519698
rs1057519698
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		T 0.700 CausalMutation CLINVAR Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359 2008
dbSNP: rs1057520019
rs1057520019
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		C 0.700 GeneticVariation CLINVAR Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359 2008
dbSNP: rs1057520019
rs1057520019
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.700 GeneticVariation UNIPROT Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359 2008
dbSNP: rs113994088
rs113994088
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		G 0.700 GeneticVariation CLINVAR Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359 2008
dbSNP: rs113994089
rs113994089
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		G 0.700 GeneticVariation CLINVAR Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359 2008
dbSNP: rs113994092
rs113994092
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		G 0.700 GeneticVariation CLINVAR Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359 2008
dbSNP: rs113994091
rs113994091
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.800 GeneticVariation UNIPROT Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. 18923523 2008
dbSNP: rs113994092
rs113994092
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.800 GeneticVariation UNIPROT Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. 18923523 2008
dbSNP: rs281864719
rs281864719
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.800 GeneticVariation UNIPROT Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. 18923523 2008
dbSNP: rs281864720
rs281864720
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.800 GeneticVariation UNIPROT Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. 18923523 2008
dbSNP: rs1057519697
rs1057519697
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		C 0.700 CausalMutation CLINVAR Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. 18923523 2008
dbSNP: rs1057520019
rs1057520019
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.700 GeneticVariation UNIPROT Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. 18923523 2008
dbSNP: rs113994087
rs113994087
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		T 0.700 CausalMutation CLINVAR Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. 18923523 2008
dbSNP: rs281864719
rs281864719
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		G 0.700 GeneticVariation CLINVAR Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. 18923523 2008
dbSNP: rs281864719
rs281864719
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		C 0.700 CausalMutation CLINVAR Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. 18923523 2008
dbSNP: rs863225285
rs863225285
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2749484
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO 		G 0.700 CausalMutation CLINVAR Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. 18923523 2008
dbSNP: rs113994091
rs113994091
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.800 GeneticVariation UNIPROT Activating mutations in ALK provide a therapeutic target in neuroblastoma. 18923525 2008
dbSNP: rs113994092
rs113994092
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease:
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.800 GeneticVariation UNIPROT Activating mutations in ALK provide a therapeutic target in neuroblastoma. 18923525 2008