DisGeNET - a database of gene-disease associations

FUS, FUS RNA binding protein, 2521

N. diseases: 301; N. variants: 39

Disease: Juvenile amyotrophic lateral sclerosis ×

Variant: rs886041390 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs886041390

Entrez Id:	2521
Gene Symbol:	FUS

FUS

CUI:	C3468114
Disease:

Juvenile amyotrophic lateral sclerosis

0.010

GeneticVariation

BEFREE

P525L FUS mutation is consistently associated with a severe form of juvenile amyotrophic lateral sclerosis.

21907581

2012