GNAS, GNAS complex locus, 2778

N. diseases: 536; N. variants: 61
Disease: Breast Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1369025856
rs1369025856
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE Recently the first somatic mutation, arginine(243) → histidine (R243H) in the GNAO1 (Gαo) gene was identified in breast carcinomas and shown to promote oncogenic transformation when introduced into cells. 21317923 2011