rs2057482
|
HIF1A;HIF1A-AS2;HIF1A-AS3
|
Malignant neoplasm of prostate
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the combined variant genotypes of rs2057482 and rs11549467 were associated with increased PCa risk (OR=2.10; 95%CI=1.23-3.57 among subjects carrying three or more risk alleles).
|
23042446 |
2012 |
rs11549467
|
HIF1A;HIF1A-AS3
|
Malignant neoplasm of prostate
|
|
0.040 |
GeneticVariation |
BEFREE |
The current findings suggest that HIF1A P582S polymorphism correlates with urinary cancers risk in Caucasian population, while A588T polymorphism may increase the risk of urinary cancers in Asian population and prostate cancer.
|
23723982 |
2013 |
rs11549467
|
HIF1A;HIF1A-AS3
|
Malignant neoplasm of prostate
|
|
0.040 |
GeneticVariation |
BEFREE |
However, the combined variant genotypes of rs2057482 and rs11549467 were associated with increased PCa risk (OR=2.10; 95%CI=1.23-3.57 among subjects carrying three or more risk alleles).
|
23042446 |
2012 |
rs11549467
|
HIF1A;HIF1A-AS3
|
Malignant neoplasm of prostate
|
|
0.040 |
GeneticVariation |
BEFREE |
In previous studies, the C1772T (P582S) or the G1790A (A588T) polymorphisms of the HIF-1alpha gene have been identified in renal cell carcinoma, head and neck and esophageal squamous cell carcinomas as well as colorectal and prostate cancers.
|
18949419 |
2008 |
rs11549467
|
HIF1A;HIF1A-AS3
|
Malignant neoplasm of prostate
|
|
0.040 |
GeneticVariation |
BEFREE |
No significant differences were found between the frequencies of A588T mutation in prostate cancer patients and controls.
|
16998808 |
2007 |
rs11549465
|
HIF1A;HIF1A-AS3
|
Malignant neoplasm of prostate
|
|
0.060 |
GeneticVariation |
BEFREE |
Our findings indicate that HIF1A rs11549465 polymorphism may not independently play a significant role in the occurrence of prostate cancer.
|
28415653 |
2017 |
rs11549465
|
HIF1A;HIF1A-AS3
|
Malignant neoplasm of prostate
|
|
0.060 |
GeneticVariation |
BEFREE |
The HIF1A +1772 C>T (rs11549465) polymorphism was genotyped, using DNA isolated from peripheral blood, in 1490 male subjects (754 with prostate cancer and 736 controls cancer-free) through Real-Time PCR.
|
24090974 |
2014 |
rs11549465
|
HIF1A;HIF1A-AS3
|
Malignant neoplasm of prostate
|
|
0.060 |
GeneticVariation |
BEFREE |
The current findings suggest that HIF1A P582S polymorphism correlates with urinary cancers risk in Caucasian population, while A588T polymorphism may increase the risk of urinary cancers in Asian population and prostate cancer.
|
23723982 |
2013 |
rs11549465
|
HIF1A;HIF1A-AS3
|
Malignant neoplasm of prostate
|
|
0.060 |
GeneticVariation |
BEFREE |
No altered PCa risk was associated with the rs11549465 and rs2057482 polymorphism.
|
23042446 |
2012 |
rs11549465
|
HIF1A;HIF1A-AS3
|
Malignant neoplasm of prostate
|
|
0.060 |
GeneticVariation |
BEFREE |
In previous studies, the C1772T (P582S) or the G1790A (A588T) polymorphisms of the HIF-1alpha gene have been identified in renal cell carcinoma, head and neck and esophageal squamous cell carcinomas as well as colorectal and prostate cancers.
|
18949419 |
2008 |
rs11549465
|
HIF1A;HIF1A-AS3
|
Malignant neoplasm of prostate
|
|
0.060 |
GeneticVariation |
BEFREE |
Our data suggest that homozygous HIF1A P582S mutation confers significant susceptibility to prostate cancer.
|
16998808 |
2007 |