|
rs9274407
|
HLA-DQB1
|
Chemical and Drug Induced Liver Injury
|
|
0.800 |
GeneticVariation |
GWASCAT |
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles.
|
21570397 |
2011 |
|
rs9274407
|
HLA-DQB1
|
Chemical and Drug Induced Liver Injury
|
|
0.800 |
GeneticVariation |
GWASDB |
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles.
|
21570397 |
2011 |
|
rs1770
|
HLA-DQB1;HLA-DQB1-AS1
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.710 |
GeneticVariation |
BEFREE |
We identified four T1D risk loci reaching genome-wide significance in the Chinese Han population, including two novel loci, rs4320356 near <i>BTN3A1</i> (odds ratio [OR] 1.26, <i>P</i> = 2.70 × 10<sup>-8</sup>) and rs3802604 in <i>GATA3</i> (OR 1.24, <i>P</i> = 2.06 × 10<sup>-8</sup>), and two previously reported loci, rs1770 in MHC (OR 4.28, <i>P</i> = 2.25 × 10<sup>-232</sup>) and rs705699 in <i>SUOX</i> (OR 1.46, <i>P</i> = 7.48 × 10<sup>-20</sup>).
|
31152121 |
2019 |
|
rs1063355
|
HLA-DQB1;HLA-DQB1-AS1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
|
19503088 |
2009 |
|
rs1063355
|
HLA-DQB1;HLA-DQB1-AS1
|
Crohn Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
|
23266558 |
2013 |
|
rs1063355
|
HLA-DQB1;HLA-DQB1-AS1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
|
rs201386475
|
HLA-DQB1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs2515895
|
HLA-DQB1;HLA-DQB1-AS1
|
Sarcoidosis
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |
|
rs2854272
|
HLA-DQB1
|
Sarcoidosis
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |
|
rs2854275
|
HLA-DQB1;HLA-DQB1-AS1
|
Major Depressive Disorder
|
|
0.700 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
rs2854275
|
HLA-DQB1;HLA-DQB1-AS1
|
Asthma
|
|
0.700 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
rs28724231
|
HLA-DQB1;HLA-DQB1-AS1
|
Arthritis, Psoriatic
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.
|
30552173 |
2019 |
|
rs3189152
|
HLA-DQB1
|
Hepatitis B
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.
|
23760081 |
2013 |
|
rs3828800
|
HLA-DQB1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs3891175
|
HLA-DQB1
|
Autoimmune Chronic Hepatitis
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
|
28779025 |
2018 |
|
rs3891175
|
HLA-DQB1
|
Cholangitis, Sclerosing
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
|
28779025 |
2018 |
|
rs3891175
|
HLA-DQB1
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs3891175
|
HLA-DQB1
|
Autoimmune Hepatitis with Centrilobular Necrosis
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
|
28779025 |
2018 |
|
rs4988888
|
HLA-DQB1
|
Sarcoidosis
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |
|
rs9274299
|
HLA-DQB1
|
Schizophrenia
|
|
0.700 |
GeneticVariation |
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
rs9274299
|
HLA-DQB1
|
Child Development Disorders, Pervasive
|
|
0.700 |
GeneticVariation |
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
rs9274407
|
HLA-DQB1
|
Liver carcinoma
|
|
0.700 |
GeneticVariation |
GWASDB |
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma.
|
23242368 |
2013 |
|
rs9274614
|
HLA-DQB1
|
Lymphoma, Follicular
|
|
0.700 |
GeneticVariation |
GWASDB |
A meta-analysis of genome-wide association studies of follicular lymphoma.
|
23025665 |
2012 |
|
rs9282114
|
HLA-DQB1
|
Sarcoidosis
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |
|
rs1063348
|
HLA-DQB1;HLA-DQB1-AS1
|
Steroid-sensitive nephrotic syndrome
|
|
0.010 |
GeneticVariation |
BEFREE |
Increased burden of risk alleles across independent loci was associated with higher odds of SSNS, with younger age of onset across all cohorts, and with increased odds of complete remission across histologies in NEPTUNE children. rs1063348 associated with decreased glomerular expression of HLA-DRB1, HLA-DRB5, and HLA-DQB1.<b>Conclusions</b> Transethnic GWAS empowered discovery of three independent risk SNPs for pediatric SSNS.
|
29903748 |
2018 |