HMGB1, high mobility group box 1, 3146

N. diseases: 724; N. variants: 10
Disease: Ischemic stroke ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2249825
rs2249825
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
CUI: C0948008
Disease:
Ischemic stroke 		0.010 GeneticVariation BEFREE We found that the rs2070600 variant of <i>RAGE</i> was associated with an increased risk of IS (OR = 1.19, 95% CI: 1.02-1.38, P = 0.043), whereas the rs2249825 variant of <i>HMGB1</i> was associated with a decreased risk of IS (OR = 0.83, 95% CI: 0.71-0.98, P = 0.041). 29245967 2017