MAF of G2548A was 42.8% in obese and 30.1% in controls (<i>P</i>=5.7 × 10<sup>-5</sup>), it showed association with weight, body mass index (BMI), waist circumference (WC), high density lipoprotein cholesterol (HDL-c) and leptin, Gln223Arg had MAF 32% in obese and 18.7% in controls (<i>P</i>=5.4 × 10<sup>-6</sup>), it showed association with fasting plasma glucose (FPG) and all lipid traits, Ala54Thr had MAF 42.4% in obese and 33.1% (<i>P</i>=0.002), it showed association with none of the tested parameters. rs9939609 MAF was 26.6%, and showed association with none of the tested parameters. rs1802295 (<i>P</i>=0.002); rs7178572 (<i>P</i>=0.007); rs2028299 (<i>P</i>=0.04); rs4812829 (<i>P</i>=0.02) showed significant while rs3923113 and rs16861329 did not show a significant association (<i>P</i>=0.20 and <i>P</i>=0.3, respectively) with obesity.
The aim of the current study was to analyze the effect of six type II diabetes GWAS loci rs3923113 (GRB14), rs16861329 (ST6GAL1), rs1802295 (VPS26A), rs7178572 (HMG20A), rs2028299 (AP3S2) and rs4812829 (HNF4A), and an FTO polymorphism (rs9939609) on obesity.