rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.
24728327
2014
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
The UMD-APC database, a model of nation-wide knowledge base: update with data from 3,581 variations.
24599579
2014
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
ACMG technical standards and guidelines for genetic testing for inherited colorectal cancer (Lynch syndrome, familial adenomatous polyposis, and MYH-associated polyposis).
24310308
2014
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
Colorectal tumors from APC*I1307K carriers principally harbor somatic APC mutations outside the A8 tract.
24416237
2014
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
SusceptibilityMutation
CLINVAR
APC polymorphisms and the risk of colorectal neoplasia: a HuGE review and meta-analysis.
23576677
2013
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
SusceptibilityMutation
CLINVAR
The APC p.I1307K polymorphism is a significant risk factor for CRC in average risk Ashkenazi Jews.
23896379
2013
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
The APC p.I1307K polymorphism is a significant risk factor for CRC in average risk Ashkenazi Jews.
23896379
2013
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
APC polymorphisms and the risk of colorectal neoplasia: a HuGE review and meta-analysis.
23576677
2013
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes.
22703879
2012
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
No evidence of the APC D1822V missense variant's pathogenicity in Tunisian patients with sporadic colorectal cancer.
18343606
2009
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
How the I1307K adenomatous polyposis coli gene variant contributes in the assessment of risk of colorectal cancer, but not stomach cancer, in a Turkish population.
17854661
2007
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
Colonic adenomas do not cosegregate with the I1307K APC missense mutation in an Israeli non-Ashkenazi family.
15712637
2005
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.
11001924
2000
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.
9724771
1998
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
SusceptibilityMutation
CLINVAR
Somatic instability of the APC I1307K allele in colorectal neoplasia.
9751605
1998
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
GeneticVariation
CLINVAR
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC.
9288102
1997
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
SusceptibilityMutation
CLINVAR
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC.
9288102
1997
rs1801155
×
Entrez Id:
324
Gene Symbol:
APC
APC
Polyposis, Adenomatous Intestinal
A
0.700
CausalMutation
CLINVAR