BIRC5, baculoviral IAP repeat containing 5, 332

N. diseases: 199; N. variants: 11
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C1306459
Disease:
Primary malignant neoplasm
0.080 GeneticVariation BEFREE Overall, significantly increased cancer risk was associated with survivin rs9904341 polymorphism when all studies were pooled (CC vs. GG: OR = 1.36, 95 % CI = 1.09-1.69; P heterogeneity < 0.001; CC vs GC/GG: OR = 1.32, 95 % CI = 1.11-1.57; P heterogeneity < 0.001). 24096544 2014
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0006826
Disease:
Malignant Neoplasms
0.080 GeneticVariation BEFREE Overall, significantly increased c</span>ancer risk was associated with survivin rs9904341 polymorphism when all studies were pooled (CC vs. GG: OR = 1.36, 95 % CI = 1.09-1.69; P heterogeneity < 0.001; CC vs GC/GG: OR = 1.32, 95 % CI = 1.11-1.57; P heterogeneity < 0.001). 24096544 2014
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder
0.020 GeneticVariation BEFREE Stratified analysis by cancer type revealed that the survivin rs9904341 polymorphism may increase the risk of colorectal cancer, renal cell cancer, gastric cancer, and bladder cancer. 24096544 2014
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0005695
Disease:
Bladder Neoplasm
0.010 GeneticVariation BEFREE Stratified analysis by cancer type revealed that the survivin rs9904341 polymorphism may increase the risk of colorectal cancer, renal cell cancer, gastric cancer, and bladder cancer. 24096544 2014
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0009402
Disease:
Colorectal Carcinoma
0.010 GeneticVariation BEFREE Stratified analysis by cancer type revealed that the survivin rs9904341 polymorphism may increase the risk of colorectal cancer, renal cell cancer, gastric cancer, and bladder cancer. 24096544 2014
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C4722085
Disease:
Malignant neoplasm of colon and/or rectum
0.010 GeneticVariation BEFREE Stratified analysis by cancer type revealed that the survivin rs9904341 polymorphism may increase the risk of colorectal cancer, renal cell cancer, gastric cancer, and bladder cancer. 24096544 2014
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0699885
Disease:
Carcinoma of bladder
0.010 GeneticVariation BEFREE Stratified analysis by cancer type revealed that the survivin rs9904341 polymorphism may increase the risk of colorectal cancer, renal cell cancer, gastric cancer, and bladder cancer. 24096544 2014
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0005684
Disease:
Malignant neoplasm of urinary bladder
0.020 GeneticVariation BEFREE The survivin rs9904341 most likely contributed to increased susceptibility to tumor in Asians as well as to gastric, colorectal and bladder cancers. 24098667 2013
dbSNP: rs1042489
rs1042489
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0027651
Disease:
Neoplasms
0.010 GeneticVariation BEFREE Moreover, the survivin rs8073069 and rs2071214 seemed to be associated with an increased tumor risk in Asians, while there was no association between the survivin rs1042489 and tumor risk. 24098667 2013
dbSNP: rs17878467
rs17878467
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0027651
Disease:
Neoplasms
0.010 GeneticVariation BEFREE As for rs17878467, the T allele might be a protective factor for tumor, especially in Asians. 24098667 2013
dbSNP: rs2071214
rs2071214
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0027651
Disease:
Neoplasms
0.010 GeneticVariation BEFREE Moreover, the survivin rs8073069 and rs2071214 seemed to be associated with an increased tumor risk in Asians, while there was no association between the survivin rs1042489 and tumor risk. 24098667 2013
dbSNP: rs8073069
rs8073069
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0027651
Disease:
Neoplasms
0.010 GeneticVariation BEFREE Moreover, the survivin rs8073069 and rs2071214 seemed to be associated with an increased tumor risk in Asians, while there was no association between the survivin rs1042489 and tumor risk. 24098667 2013
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0027651
Disease:
Neoplasms
0.010 GeneticVariation BEFREE The survivin rs9904341 most likely contributed to increased susceptibility to tumor in Asians as well as to gastric, colorectal and bladder cancers. 24098667 2013
dbSNP: rs17878467
rs17878467
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0007102
Disease:
Malignant tumor of colon
0.010 GeneticVariation BEFREE The relation between colon cancer and survivin -31 G/C (rs9904341), -241 C/T (rs17878467) and -625 C/G (rs8073069) polymorphism in promotor site of survivin gene associated with apoptosis was investigated using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. 25374237 2014
dbSNP: rs17878467
rs17878467
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0699790
Disease:
Colon Carcinoma
0.010 GeneticVariation BEFREE The relation between colon cancer and survivin -31 G/C (rs9904341), -241 C/T (rs17878467) and -625 C/G (rs8073069) polymorphism in promotor site of survivin gene associated with apoptosis was investigated using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. 25374237 2014
dbSNP: rs8073069
rs8073069
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0007102
Disease:
Malignant tumor of colon
0.010 GeneticVariation BEFREE The relation between colon cancer and survivin -31 G/C (rs9904341), -241 C/T (rs17878467) and -625 C/G (rs8073069) polymorphism in promotor site of survivin gene associated with apoptosis was investigated using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. 25374237 2014
dbSNP: rs8073069
rs8073069
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0699790
Disease:
Colon Carcinoma
0.010 GeneticVariation BEFREE The relation between colon cancer and survivin -31 G/C (rs9904341), -241 C/T (rs17878467) and -625 C/G (rs8073069) polymorphism in promotor site of survivin gene associated with apoptosis was investigated using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. 25374237 2014
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0007102
Disease:
Malignant tumor of colon
0.010 GeneticVariation BEFREE The relation between colon cancer and survivin -31 G/C (rs9904341), -241 C/T (rs17878467) and -625 C/G (rs8073069) polymorphism in promotor site of survivin gene associated with apoptosis was investigated using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. 25374237 2014
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0699790
Disease:
Colon Carcinoma
0.010 GeneticVariation BEFREE The relation between colon cancer and survivin -31 G/C (rs9904341), -241 C/T (rs17878467) and -625 C/G (rs8073069) polymorphism in promotor site of survivin gene associated with apoptosis was investigated using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. 25374237 2014
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0476089
Disease:
Endometrial Carcinoma
0.010 GeneticVariation BEFREE We observed an epistatic interaction between survivin rs9904341 CC+CG genotype and ADIPOQ rs1063539 GG genotype increasing the risk of EC compared to those with other genotypes [OR: 4.86(1.88-12.54), P=0.001]. 25613698 2015
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0007103
Disease:
Malignant neoplasm of endometrium
0.010 GeneticVariation BEFREE We observed an epistatic interaction between survivin rs9904341 CC+CG genotype and ADIPOQ rs1063539 GG genotype increasing the risk of EC compared to those with other genotypes [OR: 4.86(1.88-12.54), P=0.001]. 25613698 2015
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0001339
Disease:
Acute pancreatitis
0.010 GeneticVariation BEFREE In conclusion, we found that the survivin rs9904341 polymorphism was associated with an increased risk of acute pancreatitis. 26125713 2015
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0346647
Disease:
Malignant neoplasm of pancreas
0.010 GeneticVariation BEFREE Association between rs9904341 G<C gene polymorphism and susceptibility to pancreatic cancer in a Chinese population. 26125713 2015
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0235974
Disease:
Pancreatic carcinoma
0.010 GeneticVariation BEFREE Association between rs9904341 G<C gene polymorphism and susceptibility to pancreatic cancer in a Chinese population. 26125713 2015
dbSNP: rs9904341
rs9904341
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.020 GeneticVariation BEFREE This study was conducted to explore survivin promoter gene -31G/C (rs9904341) polymorphism and the risk of breast cancer. 29233639 2018