rs121913502
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
0.780
GeneticVariation
BEFREE
Intriguingly, the IDH2 mutation p.R140Q and novel IDH1 mutation p.I99M co-occurred in a 75-year-old patient with AML developed from myelodysplastic syndromes (MDS).
20946881
2010
rs121913502
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
MYELODYSPLASTIC SYNDROME
A
0.720
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
rs121913502
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
MYELODYSPLASTIC SYNDROME
T
0.720
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
A
0.720
CausalMutation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
T
0.720
CausalMutation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
T
0.720
CausalMutation
CLINVAR
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
25157968
2014
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
T
0.720
CausalMutation
CLINVAR
Molecular evaluation of DNMT3A and IDH1/2 gene mutation: frequency, distribution pattern and associations with additional molecular markers in normal karyotype Indian acute myeloid leukemia patients.
24606448
2014
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
0.720
GeneticVariation
BEFREE
Rapid detection of IDH2 (R140Q and R172K ) mutations in acute myeloid leukemia .
23949315
2013
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
T
0.720
CausalMutation
CLINVAR
Rapid detection of IDH2 (R140Q and R172K ) mutations in acute myeloid leukemia .
23949315
2013
rs121913502
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
MYELODYSPLASTIC SYNDROME
0.720
GeneticVariation
BEFREE
In the current study of 277 patients with MDS , IDH mutations were detected in 34 (12%) cases: 26 IDH2 (all R140Q ) and 8 IDH1 (6 R132S and 2 R132C).
22033490
2012
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
T
0.720
CausalMutation
CLINVAR
Potential application of IDH1 and IDH2 mutations as prognostic indicators in non-promyelocytic acute myeloid leukemia: a meta-analysis.
22616558
2012
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
A
0.720
CausalMutation
CLINVAR
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
22417203
2012
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
T
0.720
CausalMutation
CLINVAR
Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients.
22397365
2012
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
T
0.720
CausalMutation
CLINVAR
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
22417203
2012
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
A
0.720
CausalMutation
CLINVAR
The role of mutations in epigenetic regulators in myeloid malignancies.
22898539
2012
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
T
0.720
CausalMutation
CLINVAR
Evaluation of mutations in the isocitrate dehydrogenase genes in therapy-related and secondary acute myeloid leukaemia identifies a patient with clonal evolution to IDH2 R172K homozygosity due to uniparental disomy.
21250968
2011
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
A
0.720
CausalMutation
CLINVAR
Impact of genetic features on treatment decisions in AML.
22160010
2011
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
T
0.720
CausalMutation
CLINVAR
Impact of genetic features on treatment decisions in AML.
22160010
2011
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
T
0.720
CausalMutation
CLINVAR
The prognostic significance of IDH2 mutations in AML depends on the location of the mutation.
21596855
2011
rs121913502
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
MYELODYSPLASTIC SYNDROME
0.720
GeneticVariation
BEFREE
Intriguingly, the IDH2 mutation p.R140Q and novel IDH1 mutation p.I99M co-occurred in a 75-year-old patient with AML developed from myelodysplastic syndromes (MDS ).
20946881
2010
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
T
0.720
CausalMutation
CLINVAR
We found three missense (p.R132C, p.R132G, and p.I99M; occurred in five patients) and one silent mutation (c.315C>T; occurred in two patients) in the IDH1 gene and two missense mutations (p.R140Q and p.R172K ; occurred in four AML patients) and one silent mutation (c.435G>A) in the IDH2 gene.
20946881
2010
rs121913503
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
0.720
GeneticVariation
BEFREE
We found three missense (p.R132C, p.R132G, and p.I99M; occurred in five patients) and one silent mutation (c.315C>T; occurred in two patients) in the IDH1 gene and two missense mutations (p.R140Q and p.R172K ; occurred in four AML patients) and one silent mutation (c.435G>A) in the IDH2 gene.
20946881
2010
rs267606870
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
A
0.710
CausalMutation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
rs267606870
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
A
0.710
CausalMutation
CLINVAR
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
22417203
2012
rs267606870
×
Entrez Id:
3418
Gene Symbol:
IDH2
IDH2
Leukemia, Myelocytic, Acute
A
0.710
CausalMutation
CLINVAR
The role of mutations in epigenetic regulators in myeloid malignancies.
22898539
2012