rs2284553
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Crohn Disease
G
0.800
GeneticVariation
GWASCAT
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
26192919
2015
rs2284553
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Crohn Disease
0.800
GeneticVariation
GWASCAT
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.
28067908
2017
rs2284553
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Crohn Disease
0.800
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
rs2284553
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Crohn Disease
G
0.800
GeneticVariation
GWASCAT
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
23128233
2012
rs2284553
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Crohn Disease
G
0.800
GeneticVariation
GWASDB
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
23128233
2012
rs2834215
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Crohn Disease
0.800
GeneticVariation
GWASCAT
A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.
22936669
2013
rs2834215
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Crohn Disease
0.800
GeneticVariation
GWASDB
A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.
22936669
2013
rs74315444
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
IMMUNODEFICIENCY 28
0.800
GeneticVariation
UNIPROT
Partial interferon-gamma receptor signaling chain deficiency in a patient with bacille Calmette-Guérin and Mycobacterium abscessus infection.
10608793
2000
rs74315444
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
IMMUNODEFICIENCY 28
0.800
GeneticVariation
UNIPROT
Gains of glycosylation comprise an unexpectedly large group of pathogenic mutations.
15924140
2005
rs74315444
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
IMMUNODEFICIENCY 28
A
0.800
CausalMutation
CLINVAR
rs74315444
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
IMMUNODEFICIENCY 28
0.800
GeneticVariation
UNIPROT
Partial IFN-γR2 deficiency is due to protein misfolding and can be rescued by inhibitors of glycosylation.
23963039
2013
rs74315444
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
IMMUNODEFICIENCY 28
0.800
GeneticVariation
UNIPROT
Severe disseminated mycobacterial infection in a boy with a novel mutation leading to IFN-γR2 deficiency.
22902943
2012
rs1196094724
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
IMMUNODEFICIENCY 28
0.700
GeneticVariation
UNIPROT
rs1243506079
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
IMMUNODEFICIENCY 28
0.700
GeneticVariation
UNIPROT
rs2284553
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Inflammatory Bowel Diseases
0.700
GeneticVariation
GWASCAT
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.
28067908
2017
rs2284553
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Ulcerative Colitis
0.700
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
rs2284553
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Psoriasis
0.700
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
rs2284553
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Inflammatory Bowel Diseases
G
0.700
GeneticVariation
GWASCAT
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
26192919
2015
rs2284553
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Cholangitis, Sclerosing
0.700
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
rs2284553
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Ankylosing spondylitis
0.700
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
rs398122890
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
IMMUNODEFICIENCY 28
GTGACAA
0.700
CausalMutation
CLINVAR
rs587776822
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
IMMUNODEFICIENCY 28
C
0.700
CausalMutation
CLINVAR
rs9808753
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Psoriasis
0.700
GeneticVariation
GWASCAT
Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis.
25854761
2015
rs9808753
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Multiple Sclerosis
G
0.700
GeneticVariation
GWASCAT
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.
24076602
2013
rs1355972653
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
testicular nonseminoma
0.010
GeneticVariation
BEFREE
Analyses of haplotypes for LTA-TNF SNPs (LTA -91C>A, LTA 252A>G , TNF -863C>A, TNF -857C>T, TNF -308G>A, and -238G>A) were similarly suggestive of an association with TGCT (P = 0.06) and nonseminoma (P = 0.04), but not seminoma (P = 0.21).
17220333
2007