FAS, Fas cell surface death receptor, 355

N. diseases: 754; N. variants: 47
Disease: Primary malignant neoplasm ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2234767
rs2234767
Entrez Id: 59;355
Gene Symbol: ACTA2;FAS
ACTA2;FAS
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.020 GeneticVariation BEFREE Further studies on a larger sample size and considering gene-environment interactions should be conducted to confirm the role of FAS polymorphisms, especially rs2234767G/A, in cancer risk. 24568648 2014
dbSNP: rs2234767
rs2234767
Entrez Id: 59;355
Gene Symbol: ACTA2;FAS
ACTA2;FAS
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.020 GeneticVariation BEFREE We found that the rs2234767 G-allele was a protective factor for cancer risk (GG vs. AA: OR=0.88, 95% CI=0.79-0.98; GG+GA vs. AA: OR=0.87, 95% CI=0.79-0.96). 24568648 2014
dbSNP: rs2234767
rs2234767
Entrez Id: 59;355
Gene Symbol: ACTA2;FAS
ACTA2;FAS
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.020 GeneticVariation BEFREE FAS-1377 G/A (rs2234767) polymorphism and cancer susceptibility: a meta-analysis of 17,858 cases and 24,311 controls. 24014103 2013