IL10, interleukin 10, 3586

N. diseases: 1679; N. variants: 21
Disease: Crohn Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs145922845
rs145922845
Entrez Id: 3586;29949
Gene Symbol: IL10;IL19
IL10;IL19
CUI: C0010346
Disease:
Crohn Disease 		0.030 GeneticVariation BEFREE The interleukin-10 Gly15Arg mutation is rare in patients with Crohn's disease, and is not associated with the disease in the Netherlands. 15843082 2005
dbSNP: rs145922845
rs145922845
Entrez Id: 3586;29949
Gene Symbol: IL10;IL19
IL10;IL19
CUI: C0010346
Disease:
Crohn Disease 		0.030 GeneticVariation BEFREE A Gly15Arg mutation in the leader sequence of IL-10 was found in a multiple CD-affected family. 12825869 2003
dbSNP: rs145922845
rs145922845
Entrez Id: 3586;29949
Gene Symbol: IL10;IL19
IL10;IL19
CUI: C0010346
Disease:
Crohn Disease 		0.030 GeneticVariation BEFREE Screening of the coding region of the IL-10 gene by polymerase chain reaction--single strand conformation polymorphism (PCR-SSCP) analysis revealed a rare sequence variation in exon 1 leading to an amino acid exchange (G-->A; G15R) in two patients with CD and five healthy controls. 11271474 2000